Titlebook: Emerging Targets in Antibacterial and Antifungal Chemotherapy; Joyce A. Sutcliffe,Nafsika H. Georgopapadakou Book 1992 Routledge, Chapman

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Bacterial Pathogens for the 1990s: A Case for New Drug Development was dominated by the introduction of multiple new beta-lactams, both extended-spectrum penicillins ( . , mezlocillin, piperacillin, and azlocillin) and third-generation cephalosporins (cefotaxime, moxalactam, cefoperazone, ceftazidime, ceftizoxime, ceftriaxone, . ). The mid to latter part of the de

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DNA Replicationication in bacteria is a complex process; in . , over 30 proteins are required. It has been established biochemically and genetically that many replication genes encode products that are essential for replication (Table 3.1) Temperature-sensitive mutations in each of these genes are conditionally le

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RNA Synthesis in Bacteria: Mechanism and Regulation of Discrete Biochemical Events at Initiation andthat catalyzes transcription, locates and binds a specific promoter sequence on the template DNA, unwinds a small region surrounding a specific start site, initiates the synthesis of an RNA chain, elongates the chain to a definite stop site, and finally releases the completed transcript and dissocia