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Titlebook: Emerging Targets in Antibacterial and Antifungal Chemotherapy; Joyce A. Sutcliffe,Nafsika H. Georgopapadakou Book 1992 Routledge, Chapman

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書目名稱Emerging Targets in Antibacterial and Antifungal Chemotherapy
編輯Joyce A. Sutcliffe,Nafsika H. Georgopapadakou
視頻videohttp://file.papertrans.cn/309/308387/308387.mp4
圖書封面Titlebook: Emerging Targets in Antibacterial and Antifungal Chemotherapy;  Joyce A. Sutcliffe,Nafsika H. Georgopapadakou Book 1992 Routledge, Chapman
描述Emerging Targets in Antibacterial and Antifungal Chemotherapyoffers constructive ideas to researchers that could lead to thediscovery ofentirely new classes of drugs. The authors emphasize newtopicsrather than review work on known antibacterials andantifungals, andidentify new targets--either the rate-limitingcomponent of abiochemical pathway or a component of the pathway thatis susceptibleto a ``screening‘‘ or ``rational drug design‘‘a(chǎn)pproach. Each chapterreviews the biochemical pathway and its placein the cellular schemein order to place the target in perspective.The authors, a mixtureof academic researchers and drug-discoveryinvestigators inpharmaceutical companies, also extend thesetheoretical concerns intopractical applications and suggest usefulscreening methodologies.The importance of this subject area isdemonstrated by the increasingnumber of papers in the literaturethat point to potential targetsand screening methodologies for newantibacterials. This book alsodeals with antifungals, investigatingthe inherent limitations inexisting antifungals (many of which areextremely toxic or have onlylimited efficacy), and pointing to majordevelopments in thediscovery of novel antifung
出版日期Book 1992
關(guān)鍵詞DNA; Lipid; RNA; enzymes; lead; proteins
版次1
doihttps://doi.org/10.1007/978-1-4615-3274-3
isbn_softcover978-1-4613-6440-5
isbn_ebook978-1-4615-3274-3
copyrightRoutledge, Chapman & Hall, Inc. 1992
The information of publication is updating

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