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Titlebook: Drug Target miRNA; Methods and Protocol Marco F. Schmidt Book 2017 Springer Science+Business Media, LLC, part of Springer Nature 2017 drug

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書(shū)目名稱Drug Target miRNA
副標(biāo)題Methods and Protocol
編輯Marco F. Schmidt
視頻videohttp://file.papertrans.cn/284/283130/283130.mp4
概述Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts
叢書(shū)名稱Methods in Molecular Biology
圖書(shū)封面Titlebook: Drug Target miRNA; Methods and Protocol Marco F. Schmidt Book 2017 Springer Science+Business Media, LLC, part of Springer Nature 2017 drug
描述.This volume provides a concise and technical discussion of recently developed approaches to overcome challenges, such as pharmacodynamics and pharmacokinetics difficulties, in miRNA drug discovery. These strategies cover anti-sense agents targeting miRNA that are applied in advanced formulations or are chemically optimized to increase delivery; small molecule miRNA modulators to overcome anti-sense agents’ limitations; general enhancers of miRNA maturation; and Argonaute 2 protein and its pharmacokinetic parameters. Written in the highly successful .Methods in Molecular Biology .series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls..Cutting-edge and thorough, .Drug Target miRNA: Methods and Protocols. is a valuable resource for anyone interested in the ever-evolving field of miRNA drug discovery...?.
出版日期Book 2017
關(guān)鍵詞drug discovery; pharmacodynamics; pharmacokinetics; small molecule miRNA modulators; anti-sense agents; D
版次1
doihttps://doi.org/10.1007/978-1-4939-6563-2
isbn_softcover978-1-4939-8236-3
isbn_ebook978-1-4939-6563-2Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightSpringer Science+Business Media, LLC, part of Springer Nature 2017
The information of publication is updating

書(shū)目名稱Drug Target miRNA影響因子(影響力)




書(shū)目名稱Drug Target miRNA影響因子(影響力)學(xué)科排名




書(shū)目名稱Drug Target miRNA網(wǎng)絡(luò)公開(kāi)度




書(shū)目名稱Drug Target miRNA網(wǎng)絡(luò)公開(kāi)度學(xué)科排名




書(shū)目名稱Drug Target miRNA被引頻次




書(shū)目名稱Drug Target miRNA被引頻次學(xué)科排名




書(shū)目名稱Drug Target miRNA年度引用




書(shū)目名稱Drug Target miRNA年度引用學(xué)科排名




書(shū)目名稱Drug Target miRNA讀者反饋




書(shū)目名稱Drug Target miRNA讀者反饋學(xué)科排名




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Ausblick: Eine Roadmap der FAS 2003 – 2006olecules targeting miRNAs is a useful technology platform for anticancer drug development. Here, we describe a hepatocellular carcinoma (HCC) cell-based luciferase reporter system which could be used to screen for small molecule modulators of tumor suppressor microRNA-34a.
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Competitive Argonaute-Based RNA Immunoprecipitation for Investigation of Transcriptomic Response to elopmental therapeutics that modulate miRNAs, such as anti-miRNA oligonucleotides (anti-miR). Here, we describe a method that uses changes in Argonaute 2-RNA immunoprecipitation in response to competition by anti-miR, titrated ex vivo, as physical evidence for target validation.
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