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Titlebook: Drug Resistance in Leishmania Parasites; Consequences, Molecu Alicia Ponte-Sucre,Emilia Diaz,Maritza Padrón-Niev Book 20131st edition Sprin

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發(fā)表于 2025-3-21 19:08:36 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書(shū)目名稱(chēng)Drug Resistance in Leishmania Parasites
副標(biāo)題Consequences, Molecu
編輯Alicia Ponte-Sucre,Emilia Diaz,Maritza Padrón-Niev
視頻videohttp://file.papertrans.cn/284/283122/283122.mp4
概述Most recent and comprehensive book about Leishmania and Leishmaniasis.A useful and copious guide for clinicians and researchers alike, working in the area of infectious disease and vaccine development
圖書(shū)封面Titlebook: Drug Resistance in Leishmania Parasites; Consequences, Molecu Alicia Ponte-Sucre,Emilia Diaz,Maritza Padrón-Niev Book 20131st edition Sprin
描述One of the main problems concerning therapeutic tools for the treatment of parasitic diseases, including leishmaniasis, is that some field parasites are naturally resistant to the classical drugs; additionally, current therapies may select parasites prone to be resistant to the applied drugs. These features are (at least partially) responsible for the disappointing persistence of the disease and resultant deaths worldwide. This book provides a comprehensive view of the pathology of the disease itself, and of parasitic drug resistance, its molecular basis, consequences and possible treatments. Scientists both from academic fields and from the industry involved in biomedical research and drug design, will find in this book a valuable and fundamental guide that conveys the knowledge needed to understand and to improve the success in combating this disease worldwide.
出版日期Book 20131st edition
關(guān)鍵詞ABC Transporters; Drug Resistance; Infectious Disease; Leishmaniasis; Parasite; Vaccine Development; infec
版次1
doihttps://doi.org/10.1007/978-3-7091-1125-3
isbn_ebook978-3-7091-1125-3
copyrightSpringer-Verlag Wien 2013
The information of publication is updating

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發(fā)表于 2025-3-21 22:42:46 | 只看該作者
Molecular Evolution and Phylogeny of , e increasingly used intrinsic characters to assign . organisms into different species, they are still heirs of the first classifications based primarily on extrinsic characters. The current classification system, which proposes up to 35 species, is based on multilocus enzyme electrophoresis which is
板凳
發(fā)表于 2025-3-22 04:17:34 | 只看該作者
The Role of Reservoirs: Canine Leishmaniasisns of dogs in Asia, Europe, North Africa, and South America and is an emergent disease in North America. Domestic dogs (.) are the major hosts for these parasites and the main reservoir hosts for human visceral infection..Recent years have seen important advances on the epidemiology, pathology, and
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The Role of the Immune System in Resistance to Infectiontion. The outcome of infection depends on the parasite species as well as host genetic factors and immune competence. In order to develop a successful infection, the . must evade both the innate and adaptive immune responses. Whilst protective immunity has been driven by Th1-type T cell responses, t
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發(fā)表于 2025-3-22 15:00:53 | 只看該作者
Vaccination as a Control Measureimmune mechanisms for designing vaccines. The following section deals with the first-generation vaccines against cutaneous and visceral leishmaniasis and the candidates for second-generation vaccines, including live vaccines and vaccines based on purified and recombinant . antigens. Thereafter, the
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發(fā)表于 2025-3-23 03:25:51 | 只看該作者
Visceral Leishmaniasisnt subset of patients with visceral leishmaniasis were not responding to SbV in the State of Bihar, India. Revised recommendations using tenfold more drug provided a transient reprieve; however, a large proportion of patients in India, and to some extent in Nepal, remained unresponsive to SbV. Besid
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發(fā)表于 2025-3-23 09:31:13 | 只看該作者
American Tegumentary Leishmaniasispecies, and, thus, there are intraspecific parasitological dissimilarities that may generate different pathologies. Furthermore, in America, . spp. has diverse reservoirs (that may change continuously) and can use various vectors to infect humans and mammals. Antimonials are the drugs of choice for
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