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Titlebook: Drug Discovery in Africa; Impacts of Genomics, Kelly Chibale,Mike Davies-Coleman,Collen Masimirem Book 2012 Springer-Verlag Berlin Heidelbe

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書目名稱Drug Discovery in Africa
副標題Impacts of Genomics,
編輯Kelly Chibale,Mike Davies-Coleman,Collen Masimirem
視頻videohttp://file.papertrans.cn/284/283083/283083.mp4
概述Gives professionals and students a tool needed to facilitate drug discovery in Africa.Brings together for the first time challenges and opportunities, as well as a collection of strategies and techniq
圖書封面Titlebook: Drug Discovery in Africa; Impacts of Genomics, Kelly Chibale,Mike Davies-Coleman,Collen Masimirem Book 2012 Springer-Verlag Berlin Heidelbe
描述.Drug discovery originating in Africa has the potential to provide significantly improved treatment of endemic diseases such as malaria, tuberculosis and HIV/AIDS. This book critically reviews the current status of drug discovery research and development in Africa, for diseases that are a major threat to the health of people living in Africa. Compiled by leading African and international experts, this book presents the science and strategies of modern drug discovery. It explores how the use of natural products and traditional medicines can benefit from conventional drug discovery approaches, and proposes solutions to current technological, infrastructural, human resources, and economic challenges, which are presented when attempting to engage in full-scale drug discovery. Topics addressed are varied; from African medicinal plants to marine bioprospecting, pharmacogenetics and the use of nanotechnology. This book brings together for the first time a collection of strategies and techniques that need to be considered when developing drugs in an African setting. It is an unprecedented and truly international effort, highlighting the remarkable effort made so far in the area of drug dis
出版日期Book 2012
關鍵詞African medicinal plants; Bioprospecting; Indigenous traditional medicines; Kelly Chibale; Natural Produ
版次1
doihttps://doi.org/10.1007/978-3-642-28175-4
isbn_softcover978-3-642-43022-0
isbn_ebook978-3-642-28175-4
copyrightSpringer-Verlag Berlin Heidelberg 2012
The information of publication is updating

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Searching for Drugs That Target Multiple Receptors for Anthelmintics from African Natural Products,ape Town. Researchers at these sites can take advantage of the chemical and biological diversity found in Africa to identify lead compounds for use against parasitic nematodes of local importance. The platform employs recombinant strains of yeast which express parasite proteins in a context that mak
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Application of In Silico, In Vitro and In Vivo ADMET/PK Platforms in Drug Discovery,d if successful have, however, ensured the relevance and continued growth of the pharmaceutical industry. The major reasons for high attrition rates during drug discovery include lack of efficacy, toxicity, inadequate pharmacokinetics (PK), and market forces, factors which can be complexly interrela
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Natural Product-Based Drug Discovery Against Neglected Diseases with Special Reference to African Ne to private-sector research and development (R&D) investment. The discovery of antiparasitic new chemical entities (NCEs) based on ethnopharmacological approaches represents a major strategy for harnessing African biodiversity in the search for new drugs to combat NTDs as well as to address the ong
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,“Now I Heal with Pride”—The Application of Screens-to-Nature Technology to Indigenous Knowledge Sys innovation deficits in drug discovery. We describe the adaptation of a set of field-suitable bioassays, the “Screens-to-Nature” (STN) system, to a participatory research tool suitable for overcoming some of the difficulties in establishing cooperation between indigenous knowledge holders and scient
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