Titlebook: Development and Engineering of Dopamine Neurons; R. Jeroen Pasterkamp,Marten P. Smidt,J. Peter H. B Book 2009 The Editor(s) (if applicable

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https://doi.org/10.1007/978-90-313-6319-3nic stem cells are capable of differentiating into all cell types of the three germ layers. Self-renewal and differentiation potential are properties that make stem cells an attractive source for cell therapeutic efforts including the treatment of neurological diseases such as Parkinson’s disease (P

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,TGF-β in Dopamine Neuron Development, Maintenance and Neuroprotection,TGF-β cover regulation of proliferation, migration, differentiation, survival and death. Specifically, the effects of TGF-β on mesencephalic DAergic neurons extend from induction and specification of the dopaminergic phenotype via promotion of survival to neuroprotection in animal models of parkinso