Titlebook: Dendritic Cells and Virus Infection; Alexander Steinkasserer Book 2003 The Editor(s) (if applicable) and The Author(s), under exclusive li

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The Interaction of Immunodeficiency Viruses with Dendritic Cellsto the THP-1 cell line, the cytosolic domain of DC-SIGN is needed for HIV-1 sequestration and transmission. However, DCs lacking DC-SIGN (Langerhans cells) or expressing very low levels of DC-SIGN (rhesus macaque monocyte-derived DCs) may use additional molecules to bind and transmit immunodeficienc

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Infection of Dendritic Cells by Lymphocytic Choriomeningitis Viruse in the white pulp, and generate a robust anti-LCMV CTL response that clears the virus infection. Hence, receptor-virus interaction on DCs in vivo is an essential step in the initiation of virus-induced immunosuppression and viral persistence. Investigation into the mechanism of how virus-infected

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The Interaction Between Dendritic Cells and Herpes Simplex Virus-1nfection in lysosomal compartments. This CD83 degradation coincided with a clearly reduced T cell stimulation representing an additional new escape strategy. The functional role and the importance of CD83 are discussed in detail.

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Dendritic Cell Vaccination and Viral Infection — Animal Modelsmicrobial immune responses. Here, we discuss recent data on induction of antiviral immunity with various DC-vaccination approaches and outline future directions for the development of specific antigen targeting to DCs.

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Interplay Between Human Papillomaviruses and Dendritic Cellsrate of spontaneous rejections of high-risk HPV-infections and HPV-positive premalignant lesions indicates that in general the LC-driven antigen presentation machinery is capable of raising an effective immune defense against HPV. Epidemiological studies also reveal that a decrease in the vigilance