Titlebook: Cytokines and Colony Stimulating Factors; Methods and Protocol Dieter K?rholz,Wieland Kiess Book 2003 Humana Press 2003

小爭吵

Regulation of Autoimmune Diseasesre able to convert nontoxic prodrugs into highly cytotoxic metabolites. Thus, all cells that are transduced by suicide genes will be destroyed when the corresponding prodrug is applied. The cytotoxicity is mostly limited to transduced cells, but nontransduced cells may also be affected by the so-cal

somnambulism

Regulation of Autoimmune Diseasesg cell (APC) function, or by shifting the balance between inflammatory and regulatory cytokines (.). However, cytokine and soluble cytokine-receptor therapy have been limited by the short half-life . of these proteins and the necessity to administer relatively large boluses of recombinant proteins (

PAC

Recruiting Killer Cells for Cancer Therapy,found to have important cytostatic (.,.) as well as immunomodulatory functions (5) that have been advantageous for its clinical use both in cancer (.) and in autoimmune disease conditions such as multiple sclerosis (.,.) and, recently, in rheumatoid arthritis (.). As with many other cytokines, its l

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indoctrinate

Antibody Humanization by CDR Graftingnd immunomodulatory properties mediated through its binding to two TNF receptors (p55 and p75) (.). Signaling through the p55 receptor is primarily associated with responses such as cytotoxicity (.,.) and cytokine secretion (.) whereas the p75 receptor is responsible for lymphoproliferative signals

Fierce

Selections on Biotinylated Antigens where they usually reside in an inactive state (.). However, during this regional residency, these cells can efficiently endocytose and process antigens (.). Upon activation, they undergo a differentiation process that results in decreased antigen-processing capacity and enhanced expression of majo

Entirety

Dieter K?rholz,Wieland KiessIncludes supplementary material:

洞察力

SPER

Primary Immunodeficiencies Caused by Defects of Cytokines and Cytokine Receptors phagocytes. Cytokines and their respective receptors are intimately involved in regulating such immune responses. Their pivotal role can be illustrated in animal models for which certain cytokines or their receptors have been deleted.

PLAYS

Detection of Common Cytokine and Colony Stimulating Factor Gene PolymorphismsNA (.,.-.). In the investigation of polymorphisms, particular emphasis is directed not only at the coding region, but also at 5. and 3. regulatory regions of the candidate genes, such as the promoter which plays an important part in controlling gene transcription. The 3.-untranslated region (3.UTR)