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Titlebook: Cytokines and Colony Stimulating Factors; Methods and Protocol Dieter K?rholz,Wieland Kiess Book 2003 Humana Press 2003

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發(fā)表于 2025-3-21 19:18:42 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Cytokines and Colony Stimulating Factors
副標(biāo)題Methods and Protocol
編輯Dieter K?rholz,Wieland Kiess
視頻videohttp://file.papertrans.cn/243/242640/242640.mp4
概述Includes supplementary material:
叢書名稱Methods in Molecular Biology
圖書封面Titlebook: Cytokines and Colony Stimulating Factors; Methods and Protocol Dieter K?rholz,Wieland Kiess Book 2003 Humana Press 2003
描述The immune system is a complex network in which different cell types and soluble factors interact to efficiently eliminate various kinds of microorganisms as well as aberrant cell clones. The roots of immunologic investigations reach far into the past. In 430 BC, Thucydides reported that survivors of the plague did not present a second time with similar symptoms. The first report of a successful immu- therapy was made by Edward Jenner in 1798 who found a protective effect of cowpox vaccination against human pox. Since then, much knowledge has been accumulated; today, investigations of the molecular mechanisms of immune regulation are of central research interest. The novel insights into gene polymorphisms and gene regulation gathered from this work has improved our knowledge of individual immune reactions and risk factors in overcoming infections. Strategies to use the immune system for cancer treatment have been propelled by the discovery of divergent immunoregulatory cytokines and the introduction of new gene therapy strategies to modify immune responses. Recently, the discovery of various dendritic cells has focused attention on these cell types as central elements of the immune
出版日期Book 2003
版次1
doihttps://doi.org/10.1385/1592593453
isbn_softcover978-1-61737-318-3
isbn_ebook978-1-59259-345-3Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightHumana Press 2003
The information of publication is updating

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沙發(fā)
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Cytokines and Colony Stimulating Factors978-1-59259-345-3Series ISSN 1064-3745 Series E-ISSN 1940-6029
地板
發(fā)表于 2025-3-22 06:21:37 | 只看該作者
Alexander Zipperer,Dorothee Kretschmer phagocytes. Cytokines and their respective receptors are intimately involved in regulating such immune responses. Their pivotal role can be illustrated in animal models for which certain cytokines or their receptors have been deleted.
5#
發(fā)表于 2025-3-22 11:35:31 | 只看該作者
Alexander Zipperer,Dorothee Kretschmer phagocytes. Cytokines and their respective receptors are intimately involved in regulating such immune responses. Their pivotal role can be illustrated in animal models for which certain cytokines or their receptors have been deleted.
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Side Effects and Contraindicationshin recent years, new technology has dramatically expanded the range of parameters that can be analyzed by this technology. These include, for example, the production or secretion of soluble mediators (.-.., cell proliferation (.-.), and the detection of molecules expressed at very low density (.,.)
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發(fā)表于 2025-3-23 00:38:27 | 只看該作者
https://doi.org/10.1007/978-3-642-73276-8nd protein products (.,.). The difference between any two human genomes is estimated to be less than 0.1% (.-.). However, in light of the magnitude of the genome (approx 3.2 billion bases), the number of variations is still very large (.). The most common variation is the single-nucleotide polymorph
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發(fā)表于 2025-3-23 02:38:58 | 只看該作者
Heinz Kohler,Thomas Kieber-Emmonsrs of the TNF family (.). Like TNF and CD95 ligand (CD95L/FasL/ APO-1L), TRAIL (APO-2L) has been been shown to be a potent inducer of apoptosis in various cancer cell lines (.-.). However, in contrast to injection of TNF or CD95L, which are both lethal to mice (.), TRAIL exerts potent antitumor acti
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發(fā)表于 2025-3-23 06:27:18 | 只看該作者
Nature of the Antibody Combining Sites a component of many pathologies. Numerous angiogenic factors that regulate this complex process alone or in synergy have been identified. Vascular endothelial growth factor (VEGF) (.), basic fibroblast growth factor (bFGF) (.), transforming growth factor-α (TGF-α), platelet-derived growth factor (
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