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Titlebook: Coxiella burnetii: Recent Advances and New Perspectives in Research of the Q Fever Bacterium; Rudolf Toman,Robert A. Heinzen,Jean-Louis Me

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發(fā)表于 2025-3-21 16:28:35 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書(shū)目名稱Coxiella burnetii: Recent Advances and New Perspectives in Research of the Q Fever Bacterium
編輯Rudolf Toman,Robert A. Heinzen,Jean-Louis Mege
視頻videohttp://file.papertrans.cn/240/239230/239230.mp4
概述Provides the reader interesting insights into highly infectious intracellular pathogen Coxiella burnetii, the causative agent of Q fever, summarized by several leading groups in the field.Includes the
圖書(shū)封面Titlebook: Coxiella burnetii: Recent Advances and New Perspectives in Research of the Q Fever Bacterium; Rudolf Toman,Robert A. Heinzen,Jean-Louis Me
描述Coxiella burnetii is the etiological agent of Q fever, a zoonotic disease found worldwide. The bacterium is a fascinating example of intracellular parasitism that has uniquely evolved to thrive in the most inhospitable of cellular compartments-the phagolysosome. Understanding how C. burnetii resists the degradative functions of this vacuole, and the host cell functions coopted for successful parasitism, are central to understanding Q fever pathogenesis. Recent achievements in glycomics and proteomics are guiding development of enhanced detection schemes for the bacterium in addition to shedding light on the host immune response to the pathogen. Several chapters survey immune functions that control or potentially exacerbate Coxiella infection and delve into correlates of protective immunity elicited by vaccination. Comparative genomics is also the foundation of chapters discussing diagnostic antigen discovery and molecular typing of the bacterium, with significance for development of new clinical, epidemiologic, and forensic tools.
出版日期Book 2012
關(guān)鍵詞Coxiella burnetii; Developmental biology; Host-pathogen interactions; Immune evasion/modulation; Q fever
版次1
doihttps://doi.org/10.1007/978-94-007-4315-1
isbn_softcover978-94-007-9205-0
isbn_ebook978-94-007-4315-1
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature B.V. 201
The information of publication is updating

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, Secretion Systems,cific activities to manipulate a variety of host cell processes. Several studies have identified cohorts of . Dot/Icm effector proteins that are predicted to be involved in modulation of host cell functions. This chapter focuses specifically on these secretion systems and the role they may play during . replication in eukaryotic host cells.
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