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Titlebook: Computational Stem Cell Biology; Methods and Protocol Patrick Cahan Book 2019 Springer Science+Business Media, LLC, part of Springer Nature

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發(fā)表于 2025-3-21 18:52:24 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱Computational Stem Cell Biology
副標題Methods and Protocol
編輯Patrick Cahan
視頻videohttp://file.papertrans.cn/234/233147/233147.mp4
概述Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts
叢書名稱Methods in Molecular Biology
圖書封面Titlebook: Computational Stem Cell Biology; Methods and Protocol Patrick Cahan Book 2019 Springer Science+Business Media, LLC, part of Springer Nature
描述This volume details methods and protocols to further the study of stem cells within the computational stem cell biology (CSCB) field. Chapters are divided into four sections covering the theory and practice of modeling of stem cell behavior, analyzing single cell genome-scale measurements, reconstructing gene regulatory networks, and metabolomics. Written in the highly successful .Methods in Molecular Biology. series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls..Authoritative and cutting-edge, .Computational Stem Cell Biology: Methods and Protocols. will be an invaluable guide to researchers as they explore stem cells from the perspective of computational biology..
出版日期Book 2019
關(guān)鍵詞gene regulatory networks; single-cell transcriptome data; teratomas; engineered cells; fetal tissues
版次1
doihttps://doi.org/10.1007/978-1-4939-9224-9
isbn_softcover978-1-4939-9226-3
isbn_ebook978-1-4939-9224-9Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightSpringer Science+Business Media, LLC, part of Springer Nature 2019
The information of publication is updating

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Sustainable Tertiary Education in Asialusters of densely connected cells. This subpopulation structure represents a map of putative cell-state transitions. CellRouter implements a flow network algorithm to explore this map and reconstruct cell-state transitions in complex single-cell, multidimensional omics datasets. We describe a step-
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André Matthes,Katja Beyer,Anton Schumannl biologists. We focus specifically on the use of one tool, called Iterative Clustering and Guide-gene Selection (ICGS), which has been shown to uncover novel committed, transitional, and metastable progenitor cell states. As a component of the AltAnalyze toolkit, ICGS provides advanced methods to e
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Modeling Cellular Differentiation and Reprogramming with Gene Regulatory Networks GRN can enable control of the eventual cell fates with potential clinical applications. In this chapter, we describe our computational methodologies that we have tailor-made with purpose of applications to cell fate control. Briefly, we introduce the process of cellular differentiation and reprogra
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Computational Tools for Quantifying Concordance in Single-Cell Fateifetime and to model the deterministic effect of cell environment and inheritance, i.e., nature versus nurture. We have applied competing risks statistics, a branch of survival statistics, to quantify cell fate concordance from cell lifetime data. Competing risks modelling of cell fate concordance p
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Investigating Cell Fate Decisions with ICGS Analysis of Single Cellsl biologists. We focus specifically on the use of one tool, called Iterative Clustering and Guide-gene Selection (ICGS), which has been shown to uncover novel committed, transitional, and metastable progenitor cell states. As a component of the AltAnalyze toolkit, ICGS provides advanced methods to e
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https://doi.org/10.1007/978-1-4939-9224-9gene regulatory networks; single-cell transcriptome data; teratomas; engineered cells; fetal tissues
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