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Titlebook: Clinically Relevant Resistance in Cancer Chemotherapy; Borje Andersson,David Murray Book 2002 Springer Science+Business Media New York 200

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發(fā)表于 2025-3-23 10:49:53 | 只看該作者
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發(fā)表于 2025-3-23 16:47:43 | 只看該作者
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發(fā)表于 2025-3-23 19:57:32 | 只看該作者
Biochemical and Molecular Mechanisms of Cisplatin Resistance,ro-platinum(II); Figure 1) and its analogs fall into at least 13 clustered regions, each reflecting a distinct mechanism of action.. Many of these analogs have not been investigated in depth to unravel their fundamental mechanism of action. Indeed, almost 30 years after its clinical acceptance as a
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發(fā)表于 2025-3-24 00:27:39 | 只看該作者
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發(fā)表于 2025-3-24 05:13:03 | 只看該作者
Clinical Pharmacology of Melphalan and Its Implications for Clinical Resistance to Anticancer Agentwas reported by Bergel and Stock.. Its design was an outgrowth of studies performed during and following World War II on the mechanisms of mustard gas effects on biological systems. A summary of these early studies by Philips Philips. is of historical interest; it also serves as a model description
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發(fā)表于 2025-3-24 10:09:01 | 只看該作者
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發(fā)表于 2025-3-24 11:01:31 | 只看該作者
Genomic Approaches to Clinical Drug Resistance,vances in methodologies, such as microarray analysis for gene expression profiling, and the even larger choice ofmethods now developed for scoring genetic variations among populations, will have a profound impact on the way we understand health and disease. The drug resistance phenotype in human tum
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發(fā)表于 2025-3-24 18:06:40 | 只看該作者
Christopher Doherty,Ruby Grewal(P-gp) that are encoded by the MDR gene family. The second mechanism is exemplified by the multidrug resistance protein (MRP). Both P-gp and MRP contain ATP-binding cassettes and therefore belong to the ABC superfamily of membrane transporters
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發(fā)表于 2025-3-24 19:06:02 | 只看該作者
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