Titlebook: Clinical Trials of Antidepressants; How Changing the Mod Martin M. Katz Book 2016 The Author(s) 2016 depression.major depressive disorders.

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Prediction and Shortening the Clinical Trial: Further Advantages of the Component-Specific Model,effective trial drugs for several weeks, and will markedly reduce costs to drug companies of the clinical trial itself. This evidence will hopefully stimulate more participation of companies in antidepressant drug development.

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Introduction,s have occurred at great expense, leading to discouragement and diverting of industry to other issues. The chapter provides the rationale for why a new approach to evaluation in the trials is necessary.

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,Achieving the “Ideal” Clinical Trial: An Example of Applying the Merged Componential and Establishe two week treatment results, and the nature of the component behavioral, mood and cognitive effects. It also, introduces the capacity afforded by the model to predict the outcome of the clinical trial, based on the two week results, opening the possibility of shortening future trials.

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Why Now the Need for a New Clinical Trials Model for Antidepressants?,lier like assumptions to be wrong. When the new more comprehensive, componential trial is applied, it is also shown that new applications of the drug to the treatment of other disorders are uncovered.

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