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Titlebook: Clinical Trials of Antidepressants; How Changing the Mod Martin M. Katz Book 2016 The Author(s) 2016 depression.major depressive disorders.

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發(fā)表于 2025-3-21 19:21:39 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Clinical Trials of Antidepressants
副標(biāo)題How Changing the Mod
編輯Martin M. Katz
視頻videohttp://file.papertrans.cn/229/228270/228270.mp4
概述Identifies weaknesses in evaluating new drugs.Presents two new models for the evaluation of putative antidepressants.Appeals to clinicians, investigators, drug companies and patients.Includes suppleme
叢書名稱SpringerBriefs in Psychology
圖書封面Titlebook: Clinical Trials of Antidepressants; How Changing the Mod Martin M. Katz Book 2016 The Author(s) 2016 depression.major depressive disorders.
描述.This brief guide takes current clinical trial protocols totask and replaces them with a contemporary framework for improvingnext-generation antidepressants and their underlying science. Innovative modelsare based on a nuanced, neurologically-informed understanding of drugmechanisms and the component cognitive, mood, and behavioral aspects ofdepression. The book reconceptualizes not only the clinical trial process butthe clinical concept of depression itself as essential to bringingpharmaceutical research and development up to date, boosting efficiency andeffectiveness, finding new molecules, and reducing waste. Case studies and areview of salient depression scales illustrate the potential benefits of suchwide-scale change.?.Included in the coverage:?. Why now the need for a new clinical trials model for antidepressants?.Aims and basic requirements of clinical trials: conventional and component-specific models.. .Methods for measuring the components and the profile of drug actions: the multivantaged approach.. .Achieving the ideal clinical trial: an example of the merged componential and established models.. .Prediction and shortening the clinical trial.. .The video clinical trial.
出版日期Book 2016
關(guān)鍵詞depression; major depressive disorders; clinical trials; antidepressants; tricyclic drugs; SSRIs; clinical
版次1
doihttps://doi.org/10.1007/978-3-319-26464-6
isbn_softcover978-3-319-26463-9
isbn_ebook978-3-319-26464-6Series ISSN 2192-8363 Series E-ISSN 2192-8371
issn_series 2192-8363
copyrightThe Author(s) 2016
The information of publication is updating

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發(fā)表于 2025-3-22 00:10:51 | 只看該作者
Communications Satellite Serviceso not only achieve the primary aim of determining efficacy for a targeted disorder, but to extend results to encompass all clinical actions of the drug. It introduces the Multivantaged (MV) procedure as the methodological approach designed to enhance the amount of information from the standard trial.
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M. A. Mayo,M. E. Taliansky,C. Fritschescribes the methods and the evidence leading to the generation of the three major dimensions and the 11 behavioral and mood components, their reliabilities and validities. It utilizes figures and tables from earlier research on their development.
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2192-8363 investigators, drug companies and patients.Includes suppleme.This brief guide takes current clinical trial protocols totask and replaces them with a contemporary framework for improvingnext-generation antidepressants and their underlying science. Innovative modelsare based on a nuanced, neurological
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發(fā)表于 2025-3-22 16:29:43 | 只看該作者
https://doi.org/10.5822/978-1-61091-581-6g the secondary aims. The chapter illustrates the importance of the secondary aims for advancing science in this area, generally. It highlights that limiting the goals of these inordinately expensive experiments to the efficacy of the trial drug for one targeted disorder, is deemed wasteful and shortsighted.
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