Titlebook: Clinical Pharmacology of Antianginal Drugs; Ulrich Abshagen (Leiter Produktentwicklung Therape Book 1985 Springer-Verlag Berlin Heidelberg

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Epidemiology of Ischemic Heart Diseases our generation did between the 1950s and 1980s. Whereas, in the western hemisphere, infectious diseases came under control and, subsequently, rheumatic heart disease and syphilitic cardiovascular complications were almost eradicated, rapidly increasing “diseases of civilization” accounted for mill

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dissolution

Experimental Testing of Antianginal Drugs in Animalsficult to mimic human disease in animal experiments. Human disease is, in most instances, a multifactorial event, which runs an individual course in each patient, with a variable outcome. The aim of an experimental model of a disease should, therefore, be to include the main pathogenetic factors for

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Peripheral Circulationapplied to human limbs. The peripheral circulation could be defined in a much wider sense than this, to include the circulation through all the peripheral organ systems, but the chapter will be restricted to tests that can be used to assess skin and muscle blood flow. The human limbs are extremely w

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Organic Nitrates P. .. For this reason, literature older than 1974 which has already been covered by that volume is only used here when necessary. In the same way, topics such as historical background, chemistry and physicochemical properties or side effects of organic nitrates, which naturally have remained consta

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Molsidomineof nonbenzenoid aromatic compounds that posses a so-called mesoionic structure. Such a compound has never been introduced into therapy despite known multiple pharmacologic properties of different sydnones and sydnonimines (A. 1967; D. and D. 1962a-c; K. and R. 1967; O. et al. 1965). The drug was syn

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exceed