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Titlebook: Circulating Tumor Cells in Breast Cancer Metastatic Disease; Roberto Pi?eiro Book 2020 Springer Nature Switzerland AG 2020 circulating tum

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發(fā)表于 2025-3-21 19:08:49 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Circulating Tumor Cells in Breast Cancer Metastatic Disease
編輯Roberto Pi?eiro
視頻videohttp://file.papertrans.cn/227/226646/226646.mp4
概述This book is useful for anyone interested in the fast growing field of circulating tumor cells (CTCs).Readers will discover the fundamental knowledge about the role of CTCs in breast cancer provided b
叢書名稱Advances in Experimental Medicine and Biology
圖書封面Titlebook: Circulating Tumor Cells in Breast Cancer Metastatic Disease; Roberto Pi?eiro Book 2020 Springer Nature Switzerland AG 2020 circulating tum
描述This book is aimed to summarise the key aspects of the role of circulating tumour cells (CTCs) in breast cancer, with special attention to their contribution to tumour progression and establishment of metastatic disease. We aim to give a clear overview of the knowledge about CTCs, framed in the context of breast cancer, by analysing basic and clinical research carried out so far. In a broader sense, we will address what are the main clinical needs of this disease based on its molecular heterogeneity (subtypes) and lay out the knowledge and understanding that CTCs are giving about it and how they are contributing and can still improve the better monitoring and management of breast cancer patients. We will discuss the evidences of the use of CTCs as a tool to monitor cancer progression and therapy response, based on the prognostic and predictive value they have, as well as a tool to unravel mechanisms of resistance to therapy and to identify new biomarkers allowing to predict therapy success. Moreover, we will analyse the main aspects of ongoing clinical trials and how they can contribute to determine the clinical utility of CTCs as a breast cancer biomarker. We will also touch upon
出版日期Book 2020
關(guān)鍵詞circulating tumor cells; breast cancer; epithelial to mesenchymal transition; dormancy; metastasis; progn
版次1
doihttps://doi.org/10.1007/978-3-030-35805-1
isbn_softcover978-3-030-35807-5
isbn_ebook978-3-030-35805-1Series ISSN 0065-2598 Series E-ISSN 2214-8019
issn_series 0065-2598
copyrightSpringer Nature Switzerland AG 2020
The information of publication is updating

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發(fā)表于 2025-3-21 22:43:21 | 只看該作者
Epithelial-Mesenchymal Plasticity in Circulating Tumor Cells, the Precursors of Metastasis,s of metastasis. They exhibit dynamic oscillations in epithelial to mesenchymal plasticity and provide important opportunities for prognosis, therapy response monitoring, and targeting of metastatic disease. In this manuscript, we review the involvement of epithelial-mesenchymal plasticity in the ea
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Methodology for the Isolation and Analysis of CTCs,ast cancer mortality. Currently, liquid biopsies are gaining attention in this regard. Circulating tumor cells (CTCs), an important component of liquid biopsies, are cells shed from primary tumor that disseminate to blood circulation being responsible of distal metastasis. Hence, the study CTCs is a
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Circulating Tumor Cells: Applications for Early Breast Cancer,e intent. Despite this, some patients will relapse. The identification of patients at high risk remains an important challenge. CTCs can be useful to identify this patients, to assess tumor dynamics and to monitoring therapy. There is definitive evidence on the prognostic role of CTCs in early breas
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