| 書目名稱 | Circulating Tumor Cells in Breast Cancer Metastatic Disease |
| 編輯 | Roberto Pi?eiro |
| 視頻video | http://file.papertrans.cn/227/226646/226646.mp4 |
| 概述 | This book is useful for anyone interested in the fast growing field of circulating tumor cells (CTCs).Readers will discover the fundamental knowledge about the role of CTCs in breast cancer provided b |
| 叢書名稱 | Advances in Experimental Medicine and Biology |
| 圖書封面 |  |
| 描述 | This book is aimed to summarise the key aspects of the role of circulating tumour cells (CTCs) in breast cancer, with special attention to their contribution to tumour progression and establishment of metastatic disease. We aim to give a clear overview of the knowledge about CTCs, framed in the context of breast cancer, by analysing basic and clinical research carried out so far. In a broader sense, we will address what are the main clinical needs of this disease based on its molecular heterogeneity (subtypes) and lay out the knowledge and understanding that CTCs are giving about it and how they are contributing and can still improve the better monitoring and management of breast cancer patients. We will discuss the evidences of the use of CTCs as a tool to monitor cancer progression and therapy response, based on the prognostic and predictive value they have, as well as a tool to unravel mechanisms of resistance to therapy and to identify new biomarkers allowing to predict therapy success. Moreover, we will analyse the main aspects of ongoing clinical trials and how they can contribute to determine the clinical utility of CTCs as a breast cancer biomarker. We will also touch upon |
| 出版日期 | Book 2020 |
| 關(guān)鍵詞 | circulating tumor cells; breast cancer; epithelial to mesenchymal transition; dormancy; metastasis; progn |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-030-35805-1 |
| isbn_softcover | 978-3-030-35807-5 |
| isbn_ebook | 978-3-030-35805-1Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
| issn_series | 0065-2598 |
| copyright | Springer Nature Switzerland AG 2020 |
|Archiver|手機版|小黑屋|
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