Titlebook: Circulating Nucleic Acids in Serum and Plasma – CNAPS IX; Peter B. Gahan,Michael Fleischhacker,Bernd Schmidt Conference proceedings 2016 T

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Liquid Profiling in Lung Cancer – Quantification of Extracellular miRNAs in Bronchial Lavage bronchoscopy. Alterations in the expression of microRNAs might be useful for a discrimination of lung cancer patients from patients with a benign lung disease. We profiled extracellular microRNAs from three BL pools of lung cancer patients and three BL pools from a control group (patients with a be

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Screening of KRAS Mutation in Pre- and Post-Surgery Serum of Patients Suffering from Colon Cancer byient’s illness. The existence of KRAS driver mutations in colon cancer patients is determinant to decide their treatment and to predict their outcome. DNA is extracted automatically from 400 μL of serum using the MagNa Pure Compact with the Nucleic Acid Isolation Kit I. DNA amplification, COLD-PCR a

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Features of Circulating DNA Fragmentation in Blood of Healthy Females and Breast Cancer Patientst cancer patients were investigated. The size and concentration of circulating blood DNA were analyzed by Agilent 2100 Bioanalyser . and TaqMan PCR. The termini of circulating DNA were examined by ligation using biotinylated double-stranded oligonucleotide adapters with random 1–3 b overhangs of bot

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Implementing Non-Invasive Prenatal Diagnosis (NIPD) in a National Health Service Laboratory; From Doia, Apert syndrome), paternal mutation exclusion for cystic fibrosis and a range of bespoke tests. NIPD avoids the risks associated with invasive testing, making prenatal diagnosis more accessible to families at high genetic risk. However, the challenge remains in offering definitive diagnosis for a

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Comparative Analysis of Harmful Physical Factors Effect on the Cell Genomend the level of low-molecular-weight DNA in the blood plasma of experimental animals. The dynamics of the content of low-molecular-weight DNA increasing after exposure to low-frequency noise and ionizing radiation differs significantly. Both exposures are able to provide a direct damaging effect on