Titlebook: Circulating Nucleic Acids in Serum and Plasma – CNAPS IX; Peter B. Gahan,Michael Fleischhacker,Bernd Schmidt Conference proceedings 2016 T

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Regulation of Heat Shock Protein Responsesth inoperable tumors. Importantly, potentially targetable somatic mutations were identified in 14 of 48 patients (29.2 %) examined by cfDNA sequencing..Our two-step approach with plasma cfDNA, combining droplet digital PCR and targeted deep sequencing, is a feasible clinical approach. Assessment of

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Heat Shock Proteins in Stress in Teleostsdy indicate that the release of cfDNA from 143B cells is not a consequence of apoptosis, necrosis or a product of DNA replication, but primarily the result of actively released DNA, perhaps in association with a protein complex. Moreover, this study demonstrates the potential of . cell culture model

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Regulation of Hepatic Metabolisments with . mutated cirDNA and those with wild type cirDNA. Moreover, we have found that most of . mutated patients also presented elevated anti-p53 antibodies. The present results indicate that it is possible to detect mutated . genes with the cirDNA and that this could be used as a biomarker of tu

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Regulation of Hepatic Metabolismncer and the non-cancerous group. Further investigation by qPCR revealed five microRNAs (U6 snRNA, hsa-miR 1285, 1303, 29a-5p, 650) that were significantly up-regulated in patients with lung cancer. In bronchial lavage samples, the five microRNAs identified in this study may have a diagnostic potent

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Liver Structure and Innervation well as blunt ends were found both in plasma DNA and cell bound DNA from healthy individuals. Cell surface bound DNA from breast cancer patients mainly contains 5′-protruding ends, whereas 5′- and 3′-protruding ends are equally presented in cell free DNA from these patients. The data obtained obvio

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N. Shastri,J. Kobori,D. Munt,L. Hoode recruited 90 normal control and 30 pre-eclamptic women for the analysis of fetal PSG copy number variations (CNVs)..The identification of novel PSG CNV–disease relationships will provide not only a better understanding of the pathology of pre-eclampsia but also a novel opportunity to identify pati

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Molecular Genetics of Human Ia Antigensotypes. The fetal heterozygous genotype of homozygous pregnant women was correctly detected by COLD PCR HRM in maternal serum...-1 genotyping by HRM may be a useful aproach for genotyping all pregnant women in inexpensively. Moreover, when .-1 homozygosis was detected in a pregnant woman, fetal hete