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Titlebook: Cell Culture Techniques; Michael Aschner,Lucio Costa Book 2019Latest edition Springer Science+Business Media, LLC, part of Springer Nature

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https://doi.org/10.1007/978-94-011-5262-4At the regulatory level, systematic testing of developmental (DNT) and adult (NT) neurotoxicity is not a standard requirement within the EU legislation of chemical safety assessment, except for pesticides where NT testing is required. Both DNT and NT evaluation are only performed when triggered base
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In Vitro Blood-Brain Barrier Functional Assays in a Human iPSC-Based Model,. To carry out this role, the BBB exhibits several specialized properties, including limited permeability and active transporter function. These properties are often evaluated within in vitro BBB models, which can be utilized for high-throughput screening applications such as drug discovery. Here, w
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Oxidative Stress Signatures in Human Stem Cell-Derived Neurons,onal/glial demise resulting from exposure to environmental stressors. The cellular redox balance is maintained by a host of cellular redox systems with set points that are regulated at a subcellular level. Overwhelming deviations of these redox system balances result in oxidative stress and ultimate
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