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Titlebook: Cancer Biology and the Nuclear Envelope; Recent Advances May Eric C. Schirmer,Jose I. de las Heras Book 2014 The Editor(s) (if applicable)

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Ran GTPase in Nuclear Envelope Formation and Cancer Metastasis Ran also has been identified as an essential protein in nuclear envelope formation in eukaryotes. This mechanism is dependent on importin-β, which regulates the assembly of further complexes important in this process, such as Nup107–Nup160. A strong body of evidence is emerging implicating Ran as a
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Book 2014tecture and morphology. This volume presents a comprehensive overview of the wide range of functions recently identified for NE proteins and their relevance in cancer biology, providing molecular mechanisms and evidence of their value as prognostic and diagnostic markers and suggesting new avenues f
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Nuclear Morphometry, Epigenetic Changes, and Clinical Relevance in Prostate Cancerc (DNA methylation and histone modifications) events that dramatically and dynamically spatially change chromatin, nuclear body, and chromosome organization. In prostate cancer (CaP) there appears to be early (<50 years) versus late (>60 years) onset clinically significant cancers, and we have yet t
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