Titlebook: Brain Oncology Biology, diagnosis and therapy; An international mee M. Chatel,F. Darcel,J. Pecker Book 1987 Martinus Nijhoff Publishers, Do

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Intermediate Filaments in Fresh Frozen Tissue in Neuro-Oncology — About a Series of 1000 PeroperativIntermediate filaments represent a class of identical ultra-structure (intracellular filaments 70–100 Angstrom in diameter), yet biologically different according to their cell of origin, thus allowing the production of specific sera and monoclonal antibodies for their identification by histoimmunological technique (LAZARIDES E. 1980).

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Histological Patterns in Germ Cell TumorsTwo patients, who had a recurrence of a germ cell tumor are presented. In both cases, the first diagnosis was a benign teratoma; however, the second neuropathological diagnosis was: germinoma. This changing histological pattern of germ cell tumors is considered as a pitfall in the diagnosis and a difficulty in planning the treatment.

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Oncogenes, Growth Factors and the Pathogenesis of Human Glioma: The 1986 Engelhardt Lecturea neoplastic phenotype, are collectively called oncogenes. In recent years, it has become evident that the oncogenes do not constitute a novel genetic material in the transformed cell but represent altered versions of normal cellular genes (proto-oncogenes). The latter can be activated to transformi