Titlebook: Bortezomib in the Treatment of Multiple Myeloma; Irene M. Ghobrial,Paul G. Richardson,Kenneth C. An Book 2011 Springer Basel AG 2011 Borte

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Logistik in Dienstleistungsunternehmense findings have rightfully entrenched bortezomib as one of the most important parts of our chemotherapeutic armamentarium against multiple myeloma. In this chapter, we will review the role of bortezomib as a single-agent, and in combination with other chemotherapeutics, to combat myeloma in the rel

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Niels Bugert,Maximilian Sch?pfelr a number of ongoing studies looking at combination with conventional regimens used in MCL either with chemoimmunotherapy or as consolidation or maintenance approaches post-induction. The progress in understanding MCL biology especially regarding the heterogeneity of the disease as well as emerging

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2296-6056 h on bortezomib is a valuable source of information for researchers and clinicians from the fields of oncology and pharmacology, working either in academia or the pharmaceutical industry.978-3-7643-8948-2Series ISSN 2296-6056 Series E-ISSN 2296-6064

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Milestones in Drug Therapyhttp://image.papertrans.cn/b/image/189905.jpg

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,?konomische Gestaltungsimplikationen, protein breakdown. The primary route for degradation of intracellular proteins is the ubiquitin–proteasome pathway, in which protein substrates are linked to ubiquitin chains, which marks them for degradation by the large proteolytic complex, the 26S proteasome. It utilizes ATP to unfold protein su

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Logistik im Zwischenwerksverkehrtients and is now being used as a platform for combinations with other new agents for myeloma. In addition to its anti-myeloma effect, bortezomib also targets the bone microenvironment and can inhibit osteoclast formation and stimulate osteoblast activity in patients with myeloma. Potentially, combi

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