Titlebook: Bioinformatics Research and Development; First International Sepp Hochreiter,Roland Wagner Conference proceedings 2007 Springer-Verlag Ber

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A Soft Hierarchical Algorithm for the Clustering of Multiple Bioactive Chemical Compounds-determined threshold, into two sub clusters based on the membership values of each structure. A structure is assigned to one or both the clusters if its membership value is very high or very similar respectively. The performance of the algorithm is evaluated on two bench mark datasets and a large d

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Muscularis

Weighted Cohesiveness for Identification of Functional Modules and Their Interconnectivitythe results compared to previous work where only two of the GO aspects (molecular function and biological process) were combined. We here evaluate the predicted modules by calculating their overlap with MIPS functional complexes. In addition, we identify the “most frequent” proteins, i.e. the protei

CLOUT

Protein Remote Homology Detection Based on Binary Profilese processing, namely, the latent semantic analysis model. Testing on the SCOP 1.53 database shows that the method based on binary profiles outperforms those based on many other basic building blocks including N-grams, patters and motifs. The ROC50 score is 0.698, which is higher than other methods b

新字

Oliver Romberg,Nikolaus Hinrichschical prior distribution over interaction strenghts favours sparse networks, enabling the method to efficiently deal with small datasets..Results on a simulated dataset show that our method correctly learns network structure and model parameters even for short time series. Furthermore, we are able

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毗鄰

Oliver Romberg,Nikolaus Hinrichsh, combining a Cox regression model with a hierarchical prior distribution on the regression parameters for feature selection. This prior enables the method to efficiently deal with the low sample number, high dimensionality setting characteristic of microarray datasets. We then sample from the post

Agility

Oliver Romberg,Nikolaus Hinrichsmental PDFs and quantitative analysis of dimension and shape of probed 3D chromatin regions. Preliminary results of our numerical simulations show that the proposed numerical model is capable to reproduce experimental observations, and support the assumption of confined random folding of 3D chromati

critic

Karl-Dieter Tieste,Oliver Rombergram. The results from search methods were screened out using non-parametric binomial distribution test and compared with the binding structure from explicit molecular dynamic simulation. Both complexes from statistical selected docking simulation were found to be comparable with those from X-ray dif

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Keine Panik vor Regelungstechnik!re since every utility is automatized and collected in a single software package, so the user does not need to use different programs. Additionally, it significantly reduces the rate of data miscalculations due to human errors, very prone to occur specially in large files.