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Titlebook: Biochemistry and Molecular Genetics of Cancer Metastasis; Proceedings of the S Karoly Lapis,Lance A. Liotta,Alan S. Rabson Conference proce

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發(fā)表于 2025-3-25 04:24:34 | 只看該作者
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Morphological and Functional Alterations of Occludens, Adherens, and Gap Junctions in Cancerective barrier to diffusion. In cancer, each type of intercellular junction can differ from its normal counterpart with respect to overall size, distribution at the cell surface, level of development, and numerical density (5). These differences may account for or contribute to some properties of ma
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發(fā)表于 2025-3-25 13:07:05 | 只看該作者
Gene Products of the Major Histocompatibility Complex Control the Metastatic Phenotype of Tumor Celled as part of the enzymatic weaponry for metastatic penetration of basement membranes (3). And although the synthesis of another relevant enzyme, plasminogen activator, was higher in metastatic compared to nonmetastatic clones (4), this did not seem to represent a rate-limiting factor in the initial
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Kristin C. Thompson,Richard J. Morrismost studies on . hybridization between tumor cells and normal cells have demonstrated that the transformed and the metastatic phenotypes are recessive in nature (7, 8). Cytogenetic analyses have associated higher ploidy and more chromosomal abnormalities with advanced stages of malignancy (9). The
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https://doi.org/10.1057/9781137349521ed as part of the enzymatic weaponry for metastatic penetration of basement membranes (3). And although the synthesis of another relevant enzyme, plasminogen activator, was higher in metastatic compared to nonmetastatic clones (4), this did not seem to represent a rate-limiting factor in the initial
30#
發(fā)表于 2025-3-26 20:21:14 | 只看該作者
Conference proceedings 1986and gene products derived both from the host and the tumor cell may be required for the metastasizing tumor cell to invade, survive host defenses, travel in the circulation, arrest and adhere in the target organ, invade out, and grow as a metastatic colony. Some of these factors have recently been i
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