| 期刊全稱 | Biochemistry and Molecular Genetics of Cancer Metastasis | | 期刊簡稱 | Proceedings of the S | | 影響因子2023 | Karoly Lapis,Lance A. Liotta,Alan S. Rabson | | 視頻video | http://file.papertrans.cn/187/186680/186680.mp4 | | 學(xué)科分類 | Developments in Oncology | | 圖書封面 |  | | 影響因子 | The success rate for treatment of primary neoplasms has improved sig- nificantly due to improved surgical, radiotherapy, and chemotherapy methods, and by supportive patient care. In contrast, the treatment of cancer metastases, the cause of most cancer deaths, has not been very successful. Approximately 50% or more of patients with primary malignant neoplasms already have established metastases. Consequently, the most important problem in cancer treatment is the destruction or prevention of metastases. Metastases research has obvious clinical importance. Yet it has only been recently that investigators have attempted to study the mechanisms in- volved in this process. This is in part due to the complexity of metastases formation. A metastatic colony is the result of a complicated series of steps involving mUltiple tumor host interactions. It is expected that multiple biochemical factors and gene products derived both from the host and the tumor cell may be required for the metastasizing tumor cell to invade, survive host defenses, travel in the circulation, arrest and adhere in the target organ, invade out, and grow as a metastatic colony. Some of these factors have recently been i | | Pindex | Conference proceedings 1986 |
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