Titlebook: Bacterial Type III Protein Secretion Systems; Samuel Wagner,Jorge E. Galan Book 2020 Springer Nature Switzerland AG 2020 type three needle

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0070-217X d interest to researchers and teachers in the fields of infe.One of the most exciting developments in the field of bacterial pathogenesis in recent years is the discovery that many pathogens utilize complex nanomachines to deliver bacterially encoded effector proteins into eukaryotic and prokaryotic

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Wolfram Klosterhuber,J?rg Heining rely on a conserved protein secretion machine: the type-III secretion system. In this book chapter, we demonstrate how individually evolved mechanisms cooperate in highly versatile and robust secretion machinery to export and assemble the building blocks of those nanomachines.

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A Unified Nomenclature for Injectisome-Type Type III Secretion Systems,ed by Hueck more than 20?years ago. It found little attention for many years, but usage was sparked again by recent reviews and an international type III secretion meeting in 2016. Here, we propose that the field consistently switches to an extended version of this nomenclature to be no longer lost in translation.

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Export Mechanisms and Energy Transduction in Type-III Secretion Machines, rely on a conserved protein secretion machine: the type-III secretion system. In this book chapter, we demonstrate how individually evolved mechanisms cooperate in highly versatile and robust secretion machinery to export and assemble the building blocks of those nanomachines.

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Flagellar Hook/Needle Length Control and Secretion Control in Type III Secretion Systems,a substructure of the flagellum and the needle is a part of the needle complex. Both structures are tubular structures that have a central channel for protein secretion. Their lengths are controlled by an intriguing mechanism involving a ruler protein and a switchable gate of the protein secretion system. A model for length control is proposed.

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Emotionsregulation in der Partnerschafthways regulate solely the T3SS, others coordinately control expression of one or multiple T3SSs together with other virulence factors and fitness traits on a global scale. Over the past years, several common regulatory themes emerged, e.g., environmental control by two-component systems and carbon m

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Emotionsregulation und soziale Netzwerkeal models have been used to explain the active role of the needle in transmitting the host-cell contact signal from the tip to the base of the T3SS through conformational changes as well as during the injection of effector proteins. In this chapter, we summarize the current knowledge about the struc

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Mixed Methods in der Organisationsforschungensing and responding to environmental signals. The best-characterized injectisomes are those from ., . and . species where there is a wealth of information on the tip complex and the two translocator proteins. Of these systems, the best characterized from a secretion regulation standpoint is .. In