| 期刊全稱 | Bacterial Type III Protein Secretion Systems | | 影響因子2023 | Samuel Wagner,Jorge E. Galan | | 視頻video | http://file.papertrans.cn/181/180326/180326.mp4 | | 發(fā)行地址 | Sheds new light on type III secretion systems, which have not been the subject of a dedicated book or series in the last 10 years.Is of broad interest to researchers and teachers in the fields of infe | | 學(xué)科分類 | Current Topics in Microbiology and Immunology | | 圖書封面 |  | | 影響因子 | .One of the most exciting developments in the field of bacterial pathogenesis in recent years is the discovery that many pathogens utilize complex nanomachines to deliver bacterially encoded effector proteins into eukaryotic and prokaryotic target cells to modulate a variety of cellular functions for the pathogen’s benefit. These protein-delivery machines include the type III secretion system (T3SS), which is widespread in nature and encoded not only by bacteria pathogenic to vertebrates or plants, but also by bacteria that are symbiotic to plants or insects. Because they are essential virulence factors for many important human pathogens, these systems are emerging as a prime target for the development of new-generation, anti-infective drugs.?..This book reviews our current understanding of these intriguing injection machines as well as of the closely related T3SS that serves in flagella assembly..Individual chapters focus on regulation, assembly, structure, and function of the type III secretion machine and on the evolution of the secreted effector proteins. Given its scope, this book will appeal to a broad readership, including researchers and teachers in the fields of infectious | | Pindex | Book 2020 |
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