Titlebook: Atypical Antipsychotics; Bart A. Ellenbroek,Alexander R. Cools Book 2000 Springer Basel AG 2000 dopamine.research.schizophrenia.serotonin.

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CREST

From first to second generation antipsychoticschotic drugs that had been available for some three decades or more, most commonly perphenazine and haloperidol, with an additional 2% receiving loxapine and 13% receiving clozapine [.]. Since the identification in the 1950s of chlorpromazine as the archetype antipsychotic, a profound advance that h

浪蕩子

Animal models for schizophrenia: an introductionn identified. The main reason for this, apart from the difficulties in diagnosis (see Liddle, this volume), is the limited accessibility of the human brain. Until about 20 years ago, the investigation of the brains of patients was limited to.analysis. This technique (with a high spatial resolution)

HAIL

Oration

Regional selectivity of antipsychotic drugsfficacy, the incidence of side-effects (especially the extrapyramidal side-effects) differs between individual drugs. This has already been known for a long time, but the earlier studies were largely overlooked. Among the earlier papers were a number of clinical studies comparing several phenothiazi

CERE

碎片

Simulation models for schizophreniast decade through the recognition that not only symptoms, but also psychophysiological and psychological disturbances of the disease can be used. This has led to the development of models like prepulse inhibition (PPI), P50 gating and latent inhibition. However, the development of models simulating

Chronological

滔滔不絕地講

Dopamine receptor subtypes and schizophrenia: a clinical perspectiveal infections with viruses [.], structural abnormalities in the brain [..], receptor dysfunctions in many neurotransmission or transduction systems [..]. Concerning the latter the dopaminergic system has been implicated in schizophrenia for more than four decades. Whereas in early studies the metabo

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