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Titlebook: Apolipoprotein E and Alzheimer’s Disease; A. D. Roses,K. Weisgraber,Y. Christen Conference proceedings 1996 Springer-Verlag Berlin Heidelb

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發(fā)表于 2025-3-21 17:17:21 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
期刊全稱(chēng)Apolipoprotein E and Alzheimer’s Disease
影響因子2023A. D. Roses,K. Weisgraber,Y. Christen
視頻videohttp://file.papertrans.cn/159/158983/158983.mp4
學(xué)科分類(lèi)Research and Perspectives in Alzheimer‘s Disease
圖書(shū)封面Titlebook: Apolipoprotein E and Alzheimer’s Disease;  A. D. Roses,K. Weisgraber,Y. Christen Conference proceedings 1996 Springer-Verlag Berlin Heidelb
影響因子There is now considerable genetic evidence that the type 4 allele of the apolipoprotein E gene is a major susceptibility factor associated with late-onset Alzheimer‘s disease, the common form of the disease defined as starting after sixty years of age. The role of apolipoprotein E in normal brain metabolism and in the pathogenesis of Alzheimer‘s disease are new and exciting avenues of research. This book, written by the most outstanding scientists in this new filed, is the first presentation of results concerning the implications of apolipoprotein E on the genetics, cell biology, neuropathology, biochemistry, and therapeutic management of Alzheimer‘s disease.
Pindex Conference proceedings 1996
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Some Basic Things About Computer Arithmeticeisgraber 1994). Early studies had connected apoE to nerve regeneration following injury, where apoE participated in local capture and reutilization of neuronal membrane lipids at the injury site during the degeneration and regeneration processes (Boyles et al. 1989; Pitas et al. 1987; Skene and Sho
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https://doi.org/10.1007/b137928pared to controls. Dendritic alterations were observed as early as 4 months of age. Ultrastructural analysis revealed extensive dendritic vacuolization and disruption of the endomembrane system and cytoskeleton in apoE-deficient homozygous mice. The dendritic damage was accompanied by a decreased im
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Multiple-Precision Evaluation of Functionspressed in different cell types and appear to be differentially regulated. Two of them, the low density lipoprotein receptor related protein (LRP) and the very low density lipoprotein receptor (VLDL-r) are located in the vicinity of apoE/A. deposit in the Alzheimer’s brain. This anatomical relations
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Some Other Shift-and-Add Algorithmslipoprotein E-containing lipoproteins gives rise to complexes that are endocytosed through the LDL receptor-related protein but fails to undergo proteolytic degradation in the lysosomes. These findings may be relevant to the pathobiochemistry of Alzheimer’s disease.
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