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Titlebook: Algorithms and Methods in Structural Bioinformatics; Nurit Haspel,Filip Jagodzinski,Kevin Molloy Book 2022 The Editor(s) (if applicable) a

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發(fā)表于 2025-3-21 19:39:01 | 只看該作者 |倒序瀏覽 |閱讀模式
期刊全稱Algorithms and Methods in Structural Bioinformatics
影響因子2023Nurit Haspel,Filip Jagodzinski,Kevin Molloy
視頻videohttp://file.papertrans.cn/154/153175/153175.mp4
發(fā)行地址While there are multiple bioinformatics textbooks, very few focus solely on structural bioinformatics.The book spans a broad range of current and challenging topics in Structural bioinformatics.The bo
學科分類Computational Biology
圖書封面Titlebook: Algorithms and Methods in Structural Bioinformatics;  Nurit Haspel,Filip Jagodzinski,Kevin Molloy Book 2022 The Editor(s) (if applicable) a
影響因子The three-dimensional structure and function of molecules present many challenges and opportunities for developing an understanding of biological systems. With the increasing availability of molecular structures and the advancing accuracy of structure predictions and molecular simulations, the space for algorithmic advancement on many analytical and predictive problems is both broad and deep. To support this field, a rich set of methods and algorithms are available, addressing a variety of important problems such as protein-protein interactions, the effect of mutations on protein structure and function, and protein structure determination. Despite recent advancements in the field, in particular in protein folding with the development of AlphaFold, many problems still remain unsolved..In this book we focus on a number of topics in Structural Bioinformatics: Cryo-EM structural detection, protein conformational exploration, elucidation of molecular binding surface using geometry, the effect of mutations, insertions and deletions on protein structural stability, and protein-ligand binding..
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發(fā)表于 2025-3-22 00:07:51 | 只看該作者
Frank J. Robertz,Ruben Wickenh?user impactful, with the added goal that we sample as few decoys as possible. Previously, we sampled a subset of the ground truth and attempted a reconstruction of the data using singular value decomposition. Here we introduce a new tailored approach that decomposes the result into two components, the l
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發(fā)表于 2025-3-22 04:28:30 | 只看該作者
Book 2022rotein conformational exploration, elucidation of molecular binding surface using geometry, the effect of mutations, insertions and deletions on protein structural stability, and protein-ligand binding..
地板
發(fā)表于 2025-3-22 04:37:29 | 只看該作者
Protein-Ligand Binding with Applications in Molecular Docking,
5#
發(fā)表于 2025-3-22 12:33:22 | 只看該作者
Algorithms and Methods in Structural Bioinformatics
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發(fā)表于 2025-3-22 16:39:03 | 只看該作者
Low Rank Approximation Methods for Identifying Impactful Pairwise Protein Mutations, impactful, with the added goal that we sample as few decoys as possible. Previously, we sampled a subset of the ground truth and attempted a reconstruction of the data using singular value decomposition. Here we introduce a new tailored approach that decomposes the result into two components, the l
7#
發(fā)表于 2025-3-22 18:43:15 | 只看該作者
https://doi.org/10.1007/978-3-540-71631-0 addition to making a leap forward in accurate de novo determination, DeepTracer is remarkably fast with predictions ready in around 2 hours to trace 60,000 residues in 350 chains. Smaller proteins and complexes take only seconds or minutes. The core prediction pipeline of DeepTracer is under active development.
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發(fā)表于 2025-3-22 22:44:23 | 只看該作者
DeepTracer Web Service for Fast and Accurate De Novo Protein Complex Structure Prediction from Cryo addition to making a leap forward in accurate de novo determination, DeepTracer is remarkably fast with predictions ready in around 2 hours to trace 60,000 residues in 350 chains. Smaller proteins and complexes take only seconds or minutes. The core prediction pipeline of DeepTracer is under active development.
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發(fā)表于 2025-3-23 01:52:28 | 只看該作者
Frank J. Robertz,Ruben Wickenh?userplanations about mechanisms for achieving specificity. As a result, mechanistic explanations can potentially be extended to a large space of mutations, including the identification of those that may alter overall binding preferences.
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發(fā)表于 2025-3-23 09:04:05 | 只看該作者
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