Titlebook: Airways Smooth Muscle: Modelling the Asthmatic Response In Vivo; David Raeburn,Mark A. Giembycz Book 1996 Birkh?user Verlag 1996 Antigen.A

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晚間

Methods of Drug Administration to the Lung in Animals,n the target site is the lung, administration of drugs directly by inhalation provides a rapid onset of action, minimizes systemic exposure and reduces the amount of drug needed to achieve the required therapeutic effect. Thus, in the treatment of human bronchial asthma, bronchodilator, anti-inflamm

侵蝕

Emmenagogue

Antigen-Induced Bronchial Hyperreactivity in Rats,The likelihood of experiencing such an increase in responsiveness appears to be linked to the development of late airway responses (LAR) [1, 2]. A number of animal models of allergic bronchoconstriction have been developed in an effort to understand better the mechanism(s) of these changes [3–6]. Th

Repetitions

Virus-Induced Bronchial Hyperreactivity,hma exacerbation is most striking in children, in whom at least 30–40% [12–14] and perhaps as many as 75% of exacerbations [15] of asthma are caused by viral infections. The study of the mechanisms of virus-induced asthma attacks has led to the development of animal models.

coddle

固定某物

flamboyant

Primate Models of Asthma,ion that would be hazardous in humans [1, 2], provide tissue for study ., enable validation of data in a variety of systems, allow genetic and environmental influences to be manipulated or controlled, and facilitate the preclinical assessment of drug efficacy [2].

窩轉(zhuǎn)脊椎動(dòng)物

贊成你

Transgenic Animals and the Modelling of Asthma,uman experimentation .. Significant genetic, pathophysiological and clinical variation in the presentation and natural history of asthma complicates this experimentation. Obvious economic and ethical concerns also limit the investigation of asthma in human subjects. Nevertheless, direct examination