Titlebook: Aging Mechanisms; Longevity, Metabolis Nozomu Mori,Inhee Mook-Jung Book 2015 Springer Japan 2015 Aging.Brain.Longevity.Metabolism.Neurodege

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Aging-Related Neurodegenerative Diseases in , for the studies on neurodegenerative diseases and describe how this animal model has contributed to understanding of the mechanism of the diseases. Several features of . make it a particularly useful model for searching for genetic modifiers of disease phenotypes and for investigating the role of aging in disease development and progression.

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Conducting Polymer Nanostructures,c loss and neuronal elimination. The long-term cultured neurons in vitro seem to represent many similar aspects of physiological and possibly pathological aging that occur in vivo. The usefulness of this system as a new model for the investigation of non-replicative post-mitotic neuronal aging can be discussed.

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In Vitro Aging Revisited: The Longevity of Cultured Neuronsc loss and neuronal elimination. The long-term cultured neurons in vitro seem to represent many similar aspects of physiological and possibly pathological aging that occur in vivo. The usefulness of this system as a new model for the investigation of non-replicative post-mitotic neuronal aging can be discussed.

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Role of the Forkhead Box O Family and Neuropeptide Y in Calorie Restrictionribute to CR benefits. Recently, CR effects have been examined in individuals, leading to development of CR mimetic compounds. This review summarizes the current insights into the molecular mechanisms linking regulation of age-related genes and CR benefits in mammals.

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