Titlebook: Vasopressin; Principles and Prope Don Marshall Gash,Gerard J. Boer Book 1987 Plenum Press, New York 1987 Peptide.anatomy.brain.molecular bi

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Physiological Effects of Vasopressin on the Kidney,by which VP promotes the concentration of urine; (2) the influence of VP on renal hemodynamics; and (3) the effect of VP on the urinary excretion of sodium. The first topic has been chosen because there have been several exciting new developments in this area and the last two topics because they con

Graves’-disease

Cardiovascular Actions of Vasopressin,ed the vaso-pressor activity of pituitary gland extracts in 1895. This was soon confirmed by three other investigators (Howell, 1898; Livon, 1898; von Cyon, 1898) and Howell demonstrated that the pressor principle resided in extracts of the posterior lobe. It was from these early observations that V

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Vasopressin and Endocrine Function,rticular effects and then subsequently found to exert other effects as well, some of which turn out to be of greater physiological importance than the original ones. Vasopressin (VP) is one of the earlier examples of this phenomenon in that it was identified and named because of its vasopressor prop

athlete’s-foot

Vasopressin Receptors in the Brain and Pituitary, the hypo-thalamus-neurohypophysial system (HNS), from which VP is released into the bloodstream to exert its hormonal effects (antidiuresis, blood pressure elevation, and glycogenolysis) in the periphery (Jard, 1983; see also Chapters 9 and 10, this volume). VP released into the portal vessels of t

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Metabolic Processing of Vasopressin in the Brain and Significance of Metabolites,oteolytic processing of a large precursor, the VP-neurophysin precursor or propressophysin (Russel ., 1980; Richter, 1983; Chapter 4, this volume). Propressophysin is encoded by a single gene in bovine, rat, and man (Land .., 1982; Schmale .., 1983; Ruppert .., 1984; Sausville .., 1985). In the brai

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Vasopressin and Animal Behavior,ts potent endocrine and neural properties, should exert pronounced effects on whole-organism behavior in mammals. Circulating VP modulates somatic fluid and electrolyte levels through well-defined actions on the kidney and cardiovascular system (see Chapters 9 and 10, this volume). In addition, VP p

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Vasopressin and Human Behavior, (De Wied, 1969; see De Wied, 1983, for review). This finding has led to the suggestion that VP might have a clinical application in the treatment of human memory disorders. Unfortunately, it is not simple to state whether VP has been found effective. This is because clinical studies differ with res

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Aging of Rodent Vasopressin Systems, kidney and vasculature (Heller, 1974), the anterior pituitary (Rivier and Vale, 1985), and the liver (Hems and Whitton, 1980; Rofe and Williamson, 1983). Recent data suggest, however, that VP may have a considerably more diversified functional significance, which may be particularly relevant to agi

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Vasopressin in Relationship to Human Aging and Dementia,early as the 1930s. Observations in human subjects were crucial for both aspects. Although during that period the Scharrers proposed that neurosecretory phenomena in the central nervous system (CNS) were universal throughout the animal kingdom, the concept was not accepted until many years later, af

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Book 1987ressin, it became evident that the rapid advancements in this field made it difficult to syn- thesize the information gathered from divergent scientific disciplines into a coherent view of the biological role of vasopressin. We perceived the need for a series of critical reviews delineating this rec