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Titlebook: Vaccines against Allergies; Rudolf Valenta,Robert L. Coffman Book 2011 The Editor(s) (if applicable) and The Author(s), under exclusive li

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發(fā)表于 2025-3-21 16:54:45 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Vaccines against Allergies
編輯Rudolf Valenta,Robert L. Coffman
視頻videohttp://file.papertrans.cn/981/980204/980204.mp4
概述We are celebrating this year the hundred years′ anniversary of allergen-specific immunotherapy..In 1911 Leonard Noon published his seminal work “Prophylactic inoculation against hay fever” describing
叢書名稱Current Topics in Microbiology and Immunology
圖書封面Titlebook: Vaccines against Allergies;  Rudolf Valenta,Robert L. Coffman Book 2011 The Editor(s) (if applicable) and The Author(s), under exclusive li
描述We are celebrating this year the hundred years′ anniversary of allergen-specific immunotherapy. In 1911 Leonard Noon published his seminal work “Prophylactic inoculation against hay fever” describing his attempts to achieve active immunity against “grass pollen toxin” by administering increasing doses of grass pollen extract before the grass pollen season to allergic patients. Although it was unknown at that time that allergy represents an immunological hypersensitivity disease, the treatment was effective and many observations made by Noon remained valid until today. Today allergen-specific immunotherapy is well established as the only allergen-specific and disease-modifying treatment for IgE-mediated allergies and has long-lasting effects. In fact, more than 25% of the population suffer from IgE-mediated allergies which therefore represent a major health burden of our society, particularly because untreated allergy often progresses to severe disabling forms of disease, such as asthma and sometimes kills sensitized people through anaphylaxis.
出版日期Book 2011
關(guān)鍵詞IgE-mediated allergy; allergen specific immunotherapy; diet-specific tolerance promotion; engineered fo
版次1
doihttps://doi.org/10.1007/978-3-642-20054-0
isbn_softcover978-3-642-27100-7
isbn_ebook978-3-642-20054-0Series ISSN 0070-217X Series E-ISSN 2196-9965
issn_series 0070-217X
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE
The information of publication is updating

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Immunological Approaches for Tolerance Induction in Allergy,uch as asthma and rhinitis, the Th2 mediated phenotype is a result of loss of peripheral tolerance mechanisms. In cases such as these, approaches such as immunotherapy attempt to treat the underlying cause of allergic disease by restoring tolerance. Immunotherapy initiates many complex mechanisms wi
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Allergen-Specific Immunotherapy with Recombinant Allergens,ts. The documentation of clinical efficacy is based on crude allergenic extracts sometimes containing varying amounts of individual allergens including allergens to which the patient may not be sensitized. The introduction of recombinant allergens offer a possibility to use well-defined molecules wi
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發(fā)表于 2025-3-22 13:41:37 | 只看該作者
Vaccine Approaches for Food Allergy,ent standard of care for treatment of food allergies is limited to diligent dietary avoidance and prompt pharmacotherapy should an unexpected ingestion result in a reaction. Complex interactions between dietary antigens, the gastrointestinal flora, and the gut associated mucosal system drive host im
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發(fā)表于 2025-3-22 18:51:26 | 只看該作者
Intralymphatic Immunotherapy: From the Rationale to Human Applications,equires numerous subcutaneous injections of the allergen during 3–5?years. Over the last decade sublingual allergen applications have established as an alternative, but treatment duration could not be shortened. This review focuses on direct administration of vaccines in general and of allergens in
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