Titlebook: V Hotine-Marussi Symposium on Mathematical Geodesy; Matera, Italy June 1 Fernando Sansò Conference proceedings 2004 Springer-Verlag Berlin

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W. Kellere el- trodes” in order to expand the analyte range of ther base sensor. Smce then, the field of blosensors has greatly expanded. Some of the reasons for the expansion include both advances in signal transduction technologies and the incorporation of different biological sensing elements (Table 1). A

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Willi Freeden,Carsten Mayeralso known as Substrate-labeled Fluorescent Immunoassay) uses a modified fluorogenic enzyme substrate as a label to form a stable covalent substrate-analyte ligand conjugate. This is in contrast to most enzyme mediated immunoassays which use an enzyme rather than an enzyme substrate as the label (Ng

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P. Ditmar,R. Klees,F. Kostenkobodies, of which an extensive range exists covering a wide variety of antigens. Most of the early trials of ADEPT systems, from preclinical studies through to clinical trials, used conjugates whose attachment of antibody to enzyme was performed by chemical conjugation. Now these molecules can be joi

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