Titlebook: Upscaling of Bio-Nano-Processes; Selective Bioseparat Hermann Nirschl,Karsten Keller Book 2014 Springer-Verlag Berlin Heidelberg 2014 Biopr

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Magnetically Enhanced Centrifugation for Industrial Useial for industrial use. Magnetic particles are separated to a wire filter, from which they are cleaned by centrifugal forces to the chamber wall. The simulation of magnetic particles collected by a wire were possible by the discrete element method. The simulation shows the detachment of particles fr

enflame

enflame

Continuous Magnetic Extraction for Protein Purificationional surface groups, e.g., ion exchange ligands, serve as carriers for the target protein. Together with a mixture of thermoresponsive surfactants and binding buffer these carriers are added to the feed containing the target protein. After binding the target within minutes, the mixture is heated ab

APNEA

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Conclusionerent elements: the . of coated particles with magnetic core, a selective . which needs to be adapted to adsorb the target matter and exclude contamination, the ., which need to fit for the process in scale, budget and separation characteristics, and the . All of these elements need to fit together

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Introduction,echnology, from systems biology to bioreactor technology, have made large-scale production of sophisticated new biomolecular materials possible. However, the costs of producing these exciting new materials can be prohibitive due to separation processing, which typically constitute 80?% of the total cost of production.

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Book 2014magnetic nanoparticles and a novel technology for the upscaling of protein separation. The results come from the EU Project "MagPro2Life", which was conducted in cooperation of several european institutions and companies. .

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