| 書目名稱 | Tight Junctions in Inflammation and Cancer | | 編輯 | Ajaz A. Bhat,Mohammad Haris,Punita Dhawan | | 視頻video | http://file.papertrans.cn/926/925379/925379.mp4 | | 概述 | Covers various aspects of tight junctions, and their anatomy, biochemistry, physiology, synthesis, assembly, modulation.Reviews the relationship between tight junctions and various physiological, deve | | 圖書封面 |  | | 描述 | This book provides an updated account of tight junctions of different epithelia and endothelia and addresses their anatomy, biochemistry, physiology, synthesis, assembly, and modulation. It also discusses the relationship between molecular structure, function, regulation, posttranslational modifications of tight junction proteins and their role in gut microbiota maintenance, epithelial-mesenchymal transition, and intestinal barrier dysfunction-associated disorders important for the progression of human cancers. This book presents the pathological alterations of tight junctions at the blood-brain barrier that intensify or even initiate neurological dysfunction. Further, it reviews the significance of tight junctions and tight junction proteins in cancer development, infectious diseases, allergic reactions, and autoimmune disorders. Lastly, it highlights strategies for modulating tight junctions to enhance drug availability and organ deposition. This book is immensely useful for basic, translational, clinical, and interdisciplinary cancer researchers, practicing oncologists, and immunologists.. | | 出版日期 | Book 2023 | | 關(guān)鍵詞 | Tight junction proteins; Barrier Functions; Signalling Pathways; Posttranslational Modifications; Inflam | | 版次 | 1 | | doi | https://doi.org/10.1007/978-981-99-2415-8 | | isbn_softcover | 978-981-99-2417-2 | | isbn_ebook | 978-981-99-2415-8 | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapor |
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