| 書(shū)目名稱(chēng) | The Serotonin Receptors | | 副標(biāo)題 | From Molecular Pharm | | 編輯 | Bryan L. Roth | | 視頻video | http://file.papertrans.cn/920/919661/919661.mp4 | | 概述 | Includes supplementary material: | | 叢書(shū)名稱(chēng) | The Receptors | | 圖書(shū)封面 |  | | 描述 | A comprehensive, state-of-the-art review of our current understanding of the molecular and structural biology of 5-HT receptors and their potential use for drug discovery. The authors describe the anatomical, cellular, and subcellular distribution of 5-HT receptors and demonstrate a powerful approach to elucidating their physiological role using knockout mice in which the 5-HT receptors were deleted. They also review our understanding of the physiological role(s) of 5-HT receptors based mainly on studies performed in genetically engineered mice. Highlights include discussions of the behavioral phenotypes of 5-HT receptor knockout animals, the molecular biology and pharmacology of 5-HT receptors, and insights into the complexity of 5-HT receptor signal transduction. | | 出版日期 | Book 2006 | | 關(guān)鍵詞 | Nervous System; biology; brain; dementia; depression; drug; drug discovery; genome; molecular biology; neuroa | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-59745-080-5 | | isbn_softcover | 978-1-61737-647-4 | | isbn_ebook | 978-1-59745-080-5Series ISSN 1048-6909 Series E-ISSN 2524-6488 | | issn_series | 1048-6909 | | copyright | Humana Press 2006 |
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