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Titlebook: The Proteasome — Ubiquitin Protein Degradation Pathway; Peter Zwickl,Wolfgang Baumeister Book 2002 The Editor(s) (if applicable) and The A

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書目名稱The Proteasome — Ubiquitin Protein Degradation Pathway
編輯Peter Zwickl,Wolfgang Baumeister
視頻videohttp://file.papertrans.cn/918/917865/917865.mp4
概述Includes supplementary material:
叢書名稱Current Topics in Microbiology and Immunology
圖書封面Titlebook: The Proteasome — Ubiquitin Protein Degradation Pathway;  Peter Zwickl,Wolfgang Baumeister Book 2002 The Editor(s) (if applicable) and The A
描述This volume gives an overview of pro tea some-mediated protein degradation and the regulatory role of the ubiquitin system in cellular proteolysis. The first chapter describes the molecular evolution of the proteasome and its associated activators, i. e. , the 20S core, the base and the lid of the 19S cap, and the 11 S regulator. The ensuing chapter gives an overview of the structure and assembly of the 20S proteasome and the regulation of the archaeal proteasome by PAN. The third contribution summarizes our knowledge on the eukaryotic 26S proteasome and its regulation by the 19S regu- lator, followed by a chapter devoted to the llS regulator, which elucidates the structural basis for the 11 S-mediated activation of the 20S proteasome. The fifth chapter reviews in detail the role of the proteasome in the immune response. The subsequent chapter of the natural substrates of the gives a comprehensive description proteasome and their recognition by the enzymes of the ubiqui- tination machinery. The penultimate chapter rounds up the in- formation on intracellular distribution of proteasomes in yeast and mammalian cells, while the last contribution highlights proteasome inhibitors, tools
出版日期Book 2002
關(guān)鍵詞Cellular proteolysis; cognition; evolution; immunology; molecular evolution; peptides; proteasome inhibito
版次1
doihttps://doi.org/10.1007/978-3-642-59414-4
isbn_softcover978-3-642-63971-5
isbn_ebook978-3-642-59414-4Series ISSN 0070-217X Series E-ISSN 2196-9965
issn_series 0070-217X
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE
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978-3-642-63971-5The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE
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The Proteasome — Ubiquitin Protein Degradation Pathway978-3-642-59414-4Series ISSN 0070-217X Series E-ISSN 2196-9965
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https://doi.org/10.1007/978-3-642-59414-4Cellular proteolysis; cognition; evolution; immunology; molecular evolution; peptides; proteasome inhibito
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Book 2002prehensive description proteasome and their recognition by the enzymes of the ubiqui- tination machinery. The penultimate chapter rounds up the in- formation on intracellular distribution of proteasomes in yeast and mammalian cells, while the last contribution highlights proteasome inhibitors, tools
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The Proteasome — Ubiquitin Protein Degradation Pathway
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