| 書目名稱 | The Molecular Chaperones Interaction Networks in Protein Folding and Degradation |
| 編輯 | Walid A. Houry |
| 視頻video | http://file.papertrans.cn/915/914239/914239.mp4 |
| 概述 | First book in the Interactomics and Systems Biology book series?.Provides a comprehensive analysis of the structure and function of the diverse systems of molecular chaperones.Discusses their role in |
| 叢書名稱 | Interactomics and Systems Biology |
| 圖書封面 |  |
| 描述 | .Molecular chaperones are a fundamental group of proteins that have been identified only relatively recently. They are key components of a protein quality machinery in the cell which insures that the folding process of any newly-synthesized polypeptide chain results in the formation of a properly folded protein and that the folded protein is maintained in an active conformation throughout its functional lifetime. Molecular chaperones have been shown to play essential roles in cell viability under both normal and stress conditions. Chaperones can also assist in the unfolding and degradation of misfolded proteins and in disaggregating preformed protein aggregates. Chaperones are also involved in other cellular functions including protein translocation across membranes, vesicle fusion events, and protein secretion.??.In recent years, tremendous advances have been made in our understanding of the biology, biochemistry, and biophysics of function of molecular chaperones. In addition, recent technical developments in the fields of proteomics and genomics allowed us to obtain a global view of chaperone interaction networks. Finally, there is now a growing interest in the role of molecular |
| 出版日期 | Book 2014 |
| 關鍵詞 | interactomics; molecular chaperones; protein folding; systems biology |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-1-4939-1130-1 |
| isbn_softcover | 978-1-4939-4864-2 |
| isbn_ebook | 978-1-4939-1130-1 |
| copyright | Springer Science+Business Media New York 2014 |
|Archiver|手機版|小黑屋|
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