| 書目名稱 | The Male Role in Pregnancy Loss and Embryo Implantation Failure |
| 編輯 | Richard Bronson |
| 視頻video | http://file.papertrans.cn/914/913520/913520.mp4 |
| 概述 | Summarizes the varying factors the male contributes to pregnancy loss and embryo implantation failure, beyond chromosome abnormalities present at fertilization.Discusses seminal plasma and spermatozoa |
| 叢書名稱 | Advances in Experimental Medicine and Biology |
| 圖書封面 |  |
| 描述 | Novel topics compiled in this one-of-a-kind volume provide tantalizing hints for clinical application through future translational research. Only recently have we come to ask what role the male might play in pregnancy loss and embryo implantation failure, beyond contributing an abnormal set of paternal chromosomes at fertilization. This volume explores the recent evidence that these conditions might also be related to the transmission of previously unrecognized chromosomal micro-deletions and duplications, or via the epigenetic dysregulation of early embryonic gene function by spermatozoal microRNAs or alterations in sperm DNA methylation patterning, or by DNA damage secondary to either reactive oxygen species or environmental toxicants. In addition, the composition of seminal plasma has been found to be highly complex, containing many factors that play important roles in altering the uterine environment and the female immune system permissive of embryo implantation and?trophectoderm outgrowth leading to successful pregnancy. Coverage includes an examination of both spermatozoa and seminal fluid component factors. |
| 出版日期 | Book 2015 |
| 關(guān)鍵詞 | Embryo implantation failure; Paternal chromosomes; Seminal fluid; Seminal plasma; Spermatozoa; cytogeneti |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-319-18881-2 |
| isbn_softcover | 978-3-319-35698-3 |
| isbn_ebook | 978-3-319-18881-2Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
| issn_series | 0065-2598 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
|Archiver|手機版|小黑屋|
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