| 書目名稱 | The Interface Between Innate and Acquired Immunity |
| 編輯 | Max D. Cooper,Hilary Koprowski |
| 視頻video | http://file.papertrans.cn/913/912153/912153.mp4 |
| 叢書名稱 | Current Topics in Microbiology and Immunology |
| 圖書封面 |  |
| 描述 | All multicellular organisms may possess innate immunity mediated by defense mechanisms with which the organism is born. In recent years much has been learned about the diversity of innate immune mechanisms. A large array of naturally produced antimicrobial peptides has been de- fined. A variety of cell surface receptors that recognize common patterns displayed by infectious organisms have been identified along with the intracellular pathways that these receptors use to activate cellular defense functions. Cell surface receptors on natural killer (NK) cells have been shown to sense microbial invasion in neighboring cells, thereby setting into motion their elimination by cy- totoxic mechanisms. Other receptors have been found to facilitate phagocytosis and intracellular killing of microbes by phagocytic cells. These and other natural defense mechanisms have traditionally been viewed as the first line of body defense in vertebrate species that also possess the capacity for acquired or adaptive immunity. Sharks and all of the other jawed vertebrates generate large repertoires of T and B lymphocyte clones that display different antigen- specific receptors in the form ofT cell receptors |
| 出版日期 | Book 2002 |
| 關(guān)鍵詞 | Antigen; NK cells; T cell; T helper cells; antigen-specific receptor genes; autoimmune disease; genes; hist |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-662-04700-2 |
| isbn_softcover | 978-3-642-07682-4 |
| isbn_ebook | 978-3-662-04700-2Series ISSN 0070-217X Series E-ISSN 2196-9965 |
| issn_series | 0070-217X |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE |
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