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Titlebook: The Gliocentric Brain; Phenotype Plasticity Wolfgang Walz Book 2023 Springer Nature Switzerland AG 2023 gliosis.astrocytes.microglia.blood

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發(fā)表于 2025-3-21 17:23:31 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱The Gliocentric Brain
副標(biāo)題Phenotype Plasticity
編輯Wolfgang Walz
視頻videohttp://file.papertrans.cn/911/910625/910625.mp4
概述Up-to-date detailed overview of reactive gliosis.Approaches the topic from a biology perspective.Covers a full range of brain insults from normal aging to injury resulting in massive neuronal loss
圖書封面Titlebook: The Gliocentric Brain; Phenotype Plasticity Wolfgang Walz Book 2023 Springer Nature Switzerland AG 2023 gliosis.astrocytes.microglia.blood
描述The brain is the body’s most vulnerable organ due to the defined roles of neurons within circuits. Neurons are vastly outnumbered by microglia, astrocytes, oligodendrocytes, macrophages, cells of the blood brain barrier and invading immune cells. These cells display different grades of reactivities and interactions. They integrate their responses and not only change phenotypes but can also completely reprogram after damage to protect the neuronal complexity. The interactions of these satellite cells in the healthy brain are described as well as their roles in all major brain diseases. Special emphasis is put on immune system – brain interactions and regenerative and repair processes. The gliotic response is compared with the reactions to injuries of the skin and other organs. A final chapter addresses the definition of a cell type. It concludes that cell types can no longer be regarded as defined entities over the body’s lifetime but are prone to phenotype plasticity and even completereprograming..
出版日期Book 2023
關(guān)鍵詞gliosis; astrocytes; microglia; blood brain barrier; cell plasticity; signaling mechanisms
版次1
doihttps://doi.org/10.1007/978-3-031-48105-5
isbn_softcover978-3-031-48107-9
isbn_ebook978-3-031-48105-5
copyrightSpringer Nature Switzerland AG 2023
The information of publication is updating

書目名稱The Gliocentric Brain影響因子(影響力)




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978-3-031-48107-9Springer Nature Switzerland AG 2023
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ormal aging to injury resulting in massive neuronal lossThe brain is the body’s most vulnerable organ due to the defined roles of neurons within circuits. Neurons are vastly outnumbered by microglia, astrocytes, oligodendrocytes, macrophages, cells of the blood brain barrier and invading immune cell
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Book 2023ytes, oligodendrocytes, macrophages, cells of the blood brain barrier and invading immune cells. These cells display different grades of reactivities and interactions. They integrate their responses and not only change phenotypes but can also completely reprogram after damage to protect the neuronal
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Pepka Boyadjieva,Petya Ilieva-Trichkovaty tolerance of these cells. The majority of Na. and Cl. accumulated by the cells is compartmentalized in the vacuole, such that cytosolic levels of these ions remain near 100 mM at external NaCl concentrations of 428 mM. Current research is directed at examining changes in membrane transport proper
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Fred Sch?fer,Richard van Basshuysennhang vorgestellt, das zu den bekanntesten Modellen der Betriebswirtschaftslehre geh?rt. Es wird in Abschnitt 12.2 um einige Aspekte erweitert, soweit sie ein einzelnes Gut betreffen. Der Abschnitt 12.3 behandelt das Grundmodell im Mehrgüterfall, wenn gemeinsame Kapazit?tsrestriktionen existieren.
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