| 書目名稱 | Taurine 4 | | 副標(biāo)題 | Taurine and Excitabl | | 編輯 | Laura Corte,Ryan J. Huxtable,Keith F. Tipton | | 視頻video | http://file.papertrans.cn/901/900896/900896.mp4 | | 叢書名稱 | Advances in Experimental Medicine and Biology | | 圖書封面 |  | | 描述 | Mitochondria from mammalian tissues possess an elaborate system for 2+ 2+ transporting Ca across their inner membrane which consists of Ca import, 2+ via the Ca uniporter, in response to the mitochondrial membrane 2+ + potential ?? and of Ca release by an antiport system in exchange for H + 9,23 or Na (see Fig. l) . Because the uniporter is dependent upon the external 2+ 2+ 2+ 2+ Ca concentration ([Ca ]), mitochondria accumulate Ca until the [Ca ] o o 2+ decreases to the level at which the uniporter activity balances the Ca efflux. 2+ The [Ca ] at which the uniporter and efflux activities are equal is defined o the “setpoint” andcorresponds to values between 0.3-3μM. 2+ Figure 1. The Ca transport system of the inner membrane of mammalian mitochondria. U, + 2+ + + uniporter. I, Na -independent efflux mechanism or Ca /2H exchanger. D, Na -dependent 2+ + efflux mechanism or Ca /2Na exchanger. PTP, permeability transition pore. FP, 11 flavoprotein. ?? membrane potential. ? pH gradient. Adapted from . | | 出版日期 | Book 2002 | | 關(guān)鍵詞 | Lipid; Nutrition; Oxidation; RNA; cells; enzymes; ethanol; gene expression; metabolism; neurons; thermoregulat | | 版次 | 1 | | doi | https://doi.org/10.1007/b112581 | | isbn_softcover | 978-1-4757-7342-2 | | isbn_ebook | 978-0-306-46838-4Series ISSN 0065-2598 Series E-ISSN 2214-8019 | | issn_series | 0065-2598 | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |
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