| 書目名稱 | Targeted Therapies | | 副標(biāo)題 | Mechanisms of Resist | | 編輯 | Daniel Gioeli | | 視頻video | http://file.papertrans.cn/901/900622/900622.mp4 | | 概述 | For the physician-scientist treating patients.Describes advantages and pitfalls of experimental models currently in use.Leading edge techniques.Includes supplementary material: | | 叢書名稱 | Molecular and Translational Medicine | | 圖書封面 |  | | 描述 | .This volume explores the mechanisms of resistance to targeted therapeutics. The focus is on the cancer cell signaling network, although other mechanisms of resistance including target mutation, and new areas of study such as cancer stem cells are included..Targeted Therapies: Mechanisms of Resistance highlights examples of changes in the signaling network in response to inhibition of a signaling event and underscores the importance in having a mechanistic understanding of the signaling network in cancer for developing effective targeted cancer therapies. Moreover, cutting edge tools to analyze the cell signaling network will be discussed. This includes the leading edge of techniques as well as computational biology and systems theory. This volume provides the reader with both an overview as well as a detailed perspective on the mechanisms of resistance to targeted therapeutics and will be of great value to the oncologist, the physician-scientist treating patients and the translational scientist working on any aspect of targeted therapeutics.. | | 出版日期 | Book 2011 | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-60761-478-4 | | isbn_softcover | 978-1-61779-744-6 | | isbn_ebook | 978-1-60761-478-4Series ISSN 2197-7852 Series E-ISSN 2197-7860 | | issn_series | 2197-7852 | | copyright | Springer Science+Business Media, LLC 2011 |
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