| 書目名稱 | TGF-β Signaling | | 副標題 | Methods and Protocol | | 編輯 | Xin-Hua Feng,Pinglong Xu,Xia Lin | | 視頻video | http://file.papertrans.cn/901/900091/900091.mp4 | | 概述 | Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts | | 叢書名稱 | Methods in Molecular Biology | | 圖書封面 |  | | 描述 | .This volume details up-to-date information and attempts to take the reader into the exciting realm of TGF-β from the basic principles to the practical applications. Chapters provide basic introduction of TGF-β signaling from the cell surface to the nucleus, methods and techniques for the investigation of TGF-β signaling mechanism including receptors, Smads, intracellular kinases, microRNA, epigenetic regulation, post-translational regulations, non-Smad pathway; the physiological implications including those in cell cycle arrest, epithelial-mesenchymal transition, endothelial cells, adipogenesis, Th differentiation, stem cell, bone remodeling, ovary, zebrofish development, and frog animal capping; and the methodologies including metastasis imaging, 3D morphogenesis, membrane receptor quantification, conditional knockout, bone remodeling, kinase and phosphatase assays, BiFC interaction assays, and genome-wide siRNA screen. Written in the highly successful .Methods in Molecular Biology. series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubl | | 出版日期 | Book 2016 | | 關(guān)鍵詞 | Th differentiation; adipogenesis; bone remodeling; cell surface; epigenetic regulation; epithelial-mesenc | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4939-2966-5 | | isbn_softcover | 978-1-4939-4993-9 | | isbn_ebook | 978-1-4939-2966-5Series ISSN 1064-3745 Series E-ISSN 1940-6029 | | issn_series | 1064-3745 | | copyright | Springer Science+Business Media New York 2016 |
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