書(shū)目名稱(chēng) | T Lymphocytes as Tools in Diagnostics and Immunotoxicology |
編輯 | Stefan F. Martin |
視頻video | http://file.papertrans.cn/901/900009/900009.mp4 |
概述 | Alternative assays for the detection of contact allergens and drug metabolites.Summarizes the state-of-the art.Written by experts in the field.Includes supplementary material: |
叢書(shū)名稱(chēng) | Experientia Supplementum |
圖書(shū)封面 |  |
描述 | .This book summarizes the state-of-the art in the development of T cell-based .in vitro. assays, which offer useful tools for hazard identification, risk assessment and improvement of diagnostics. It will be of interest to scientists, the chemical and pharmaceutical industry, and regulators involved in the replacement of animal testing methods..The identification of hazardous chemicals and drugs is essential to ensuring human health. The ban on animal testing for the cosmetics industry since 2009 and international efforts to reduce and replace animal testing in research and immunotoxicology call for alternative .in vitro. methods. The most specific immune response to chemicals and drugs that cause allergic contact dermatitis, respiratory disease and adverse drug reactions is the highly antigen-specific T lymphocyte response. Therefore the use of T cells as tools for identifying contact allergens and drugs that may cause health problems is of great interest. . |
出版日期 | Book 2014 |
關(guān)鍵詞 | Contact allergen; Hypersensitivity; T cell assay |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-0348-0726-5 |
isbn_ebook | 978-3-0348-0726-5Series ISSN 1664-431X Series E-ISSN 2504-3692 |
issn_series | 1664-431X |
copyright | Springer Basel 2014 |