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Titlebook: Systems Pharmacology and Pharmacodynamics; Donald E. Mager,Holly H.C. Kimko Book 2016 American Association of Pharmaceutical Scientists 20

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發(fā)表于 2025-3-21 18:15:01 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Systems Pharmacology and Pharmacodynamics
編輯Donald E. Mager,Holly H.C. Kimko
視頻videohttp://file.papertrans.cn/885/884914/884914.mp4
概述First book that covers the expertise from systems biology and pharmacodynamics researchers in one place.Outlines how systems pharmacology should reduce the high attrition in the drug development pipel
叢書名稱AAPS Advances in the Pharmaceutical Sciences Series
圖書封面Titlebook: Systems Pharmacology and Pharmacodynamics; Donald E. Mager,Holly H.C. Kimko Book 2016 American Association of Pharmaceutical Scientists 20
描述While systems biology and pharmacodynamics have evolved in parallel,?there are significant interrelationships that can enhance drug discovery and enable optimized therapy for each patient. Systems pharmacology is the relatively new discipline?that is the?interface between these two methods. This book is the first to?cover the expertise from systems biology and pharmacodynamics researchers, describing how systems pharmacology may be developed and refined further to show practical applications in drug development. There is a growing awareness that pharmaceutical companies should reduce the high attrition in the pipeline due to insufficient efficacy or toxicity found in?proof-of-concept and/or Phase?II studies. Systems Pharmacology and Pharmacodynamics?discusses the?framework for integrating information obtained from?understanding physiological/pathological pathways (normal body function system vs. perturbed system due to disease) and pharmacological targets?in order to predict clinical efficacy and adverse events through iterations between mathematical modeling and experimentation.
出版日期Book 2016
關(guān)鍵詞PK/PD; bioinformatics; drug targets; modeling; pharmacokinetics; systems biology
版次1
doihttps://doi.org/10.1007/978-3-319-44534-2
isbn_softcover978-3-319-83074-2
isbn_ebook978-3-319-44534-2Series ISSN 2210-7371 Series E-ISSN 2210-738X
issn_series 2210-7371
copyrightAmerican Association of Pharmaceutical Scientists 2016
The information of publication is updating

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provided by prominent scholars on key texts and all texts a.Fresh translations of key texts, exhaustive coverage from Plato to Kant, and detailed commentary by expert scholars of philosophy add up to make this sourcebook the first and most comprehensive account of the history of the philosophy of m
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Donald E. Mager,Holly H. C. Kimkoy texts on philosophy of language from antiquity (500BC) to For the first time in English, this anthology offers a comprehensive selection of primary sources in the history of philosophy of language. Beginning with a detailed introduction contextualizing the subject, the editors draw out recurring t
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Saroja Ramanujan,Kapil Gadkar,Ananth Kadambierest to individuals involved in clinical practice as well as research. Understand- ing the multiple domains of functioning, evaluating characteristics of individuals in relation to others (normative assessment) as well as in relation to themselves (ipsative assessment), and charting progress or cha
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Steven Nathaniel Steinway,Rui-Sheng Wang,Reka Alberterest to individuals involved in clinical practice as well as research. Understand- ing the multiple domains of functioning, evaluating characteristics of individuals in relation to others (normative assessment) as well as in relation to themselves (ipsative assessment), and charting progress or cha
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Mehdi Bouhaddou,Marc R. Birtwistlerce book or survey of the elements/essentials of feedback control systems. The material included is a result of my development, over a period of several years, of summaries written to supplement a number of standard textbooks for undergraduate and early post-graduate courses. Those notes, plus more
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ist, critical race, and social exchange theories.Addresses s.This sourcebook is an unparalleled resource in the field of family science. It provides a comprehensive overview of both traditional and contemporary theories and methodologies to promote a greater understanding of increasingly complex fam
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