Titlebook: Synthetic Biology; Anton Glieder,Christian P. Kubicek,Michael Sauer Book 2016 Springer International Publishing Switzerland 2016 artificia

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Programming Biology: Expanding the Toolset for the Engineering of Transcription,the fields of molecular and synthetic biology have contributed both historically and presently to the state of the art in transcriptional engineering. The described tools and techniques, as well as the emerging genetic circuit engineering discipline, open the door to new advances in the fields of medical and industrial biotechnology.

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Novel DNA and RNA Elements,alkers and DNA machines are emphasized. The knowledge and experiences gained in the investigations of large numbers of natural and novel DNA and RNA parts have built the foundation for the design of new functions of polynucleotides and model-based regulation of gene and pathway expression.

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Novel DNA and RNA Elements,thesis of large oligonucleotides and double-stranded DNA parts, chip-based synthesis of DNA libraries, and a detailed understanding of fundamental biological mechanisms and increased capacities in bioinformatics enable new findings and applications..In this chapter, reengineered and model-based desi

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Protein Building Blocks and the Expansion of the Genetic Code,re but they are excluded from ribosomal translation. Nevertheless, nature exploits their vast chemical diversity for the production of highly bioactive peptides by non-ribosomal biosynthesis routes. The extraordinarily rich structural and functional repertoire of the noncanonical amino acids holds g

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Synthetic Biology for Cellular Remodelling to Elicit Industrially Relevant Microbial Phenotypes, with the industrial world being more open to this opportunity for a change. The challenge is therefore to make such processes viable and competitive. When moving from the lab to the industrial scale, the degree of complexity is increasing, and the engineered cell factories very often display emergi

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Microbial Platform Cells for Synthetic Biology,hnological aspects, the area of synthetic biology includes (1) the synthesis of genes, genomes, and life; (2) the synthesis of new metabolic pathways; (3) modular engineering of proteins; and (4) the development of biosensors, most of which can be verified in synthetic cells. To achieve the various

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